OHN2)KOH,1)KH〈excess)18-crown-6,THf,「tCICO2Me(excess〉pyridine,-78°CtortClClquinoline210°CTBNaOM1)rr)CPBA,CH2CI2,0°C2)QqHBF4,CH2CI2,rt3)B「Mg/、IVle,cecl3THF,-78°Ctort4)PdCI2(MeCN)2(1eq)DME,rtCheat,200°CEtO2C^1)TfOH,CH2CI2,0°Cpyridine2)toluene,reflux3)TBAF,H2O2DMF,55°Ctoluene-30°Ctort...

时间:2024-11-08 16:35栏目:行业资料