SHANDONGＵＮＩＶＥＲＳＩＴＹＯＦＴＥＣＨＮＯＬＯＧＹ毕业论文水热均匀沉淀法合成锶钡替代HAP的形貌与结构学院：材料科学与工程专业：材料科学与工程学生姓名：盛杰学号：0911111097指导教师：王萍2013年6月摘要羟基磷灰石（HAP）具有良好的生物活性、生物相容性和优异的吸附性能，已广泛应于生物医学、环境治理等相关领域。本文以氧化钙、磷酸、硝酸锶以及氯化钡为原料，用硝酸调控溶液的酸度，采用水热均匀沉淀法来合成Sr2+和Ba2+替代的羟基磷灰石，并对在不同条件下合成的产物进行形貌以及物相分析，以研究不同的条件对羟基磷灰石形貌的影响。通过实验得到了以下结论：(1)通过不同条件下的实验，找到了合成Sr2+替代羟基磷灰石的最佳条件，最佳条件下合成的羟基磷灰石纤维粗细均匀，长径比较好。(2)研究了不同的反应条件对Ba2+替代羟基磷灰石的影响。(3)离子替代会对晶体的晶格参数产生一定影响。(4)在不同的条件下，合成了形貌不同的羟基磷灰石，其中Sr2+替代的主要为纤维状，Ba2+替代的主要呈现为片状，有部分产物聚集为花簇状。关键词：羟基磷灰石,水热均匀沉淀法,离子替代AbstractHydroxyapatite(HAP)hasgoodbiologicalactivity,biocompatibilityandaexcellentcharacteristicofadsorption,hasbeenwidelyappliedintheareasofbiomedicalscience,environmentalmanagementandsoon.Thisthesistakescalciumoxideandphosphoricacid,strontiumnitrateandbariumchlorideasitsrawmaterials,usesnitricacidtoregulateandcontroltheacidityofthesolution,adoptshomogeneousprecipitationmethodtosynthesizehydroxyapatitewhichisreplacedbyBa2+andSr2+substitute.Thisthesisalsomakesamorphologyandphaseanalysisabouttheproductswhichissynthesizedindifferentconditions,tostudytheinfluencesofdifferentconditionsonhydroxyapatite.Themainresearchresultsareasfollows:(1)WefindtheoptimumconditionforsynthesisofSr2+substitutehydroxyapatitethroughexperimentsunderdifferentconditions,andhydroxyapatite’sfiberssynthesizedunderthebestconditionseventhickness,anditslengthdiameterisbetter.(2)TostudytheeffectsofdifferentreactionconditionsonBa2+substitutedhydroxyapatite.(3)Ionsubstitutionhasacertaineffectonthecrystallatticeparameters.(4)underdifferentconditions,differenthydroxyapatitemorphologywassynthesized.whatarereplacedbySr2+arepredominantlyintheshapeoffibrous,whatarereplacedbyBa2+replacemainlyshowassheetmaterial,andtherearepartoftheproductsgatheredintheshapeofflowers.Keywords:hydroxyapatite,homogeneousprecipitationmethod,ionsubstation目录摘要...........................................................................................................IABSTRACT（英文摘要）............................................................................II目录...........................................................................................................III第一章引言...............................................................................................11.1课题的背景、主要研究内容及意义.............................................................11.1.1课题的背景及意义................................................................................11.1.2课题的主要研究内容............................................................................11.2羟基磷灰石的组成、晶体结构及性质.........................................................11.3羟基磷灰石的用途.........................................................................................31.3.1生物材料.................................................................................................31.3.2药物载体.....................................................
