项八针联合吞咽康复训练对假性延髓麻痹吞咽-障碍患者血清VEGF、TGF-β1的影响

下载后可任意编辑项八针联合吞咽康复训练对假性延髓麻痹吞咽,障碍患者血清 VEGF、TGF-β1 的影响项八针联合吞咽康复训练对假性延髓麻痹吞咽,障碍患者血清 VEGF、TGF-β1 的影响 王罗丹 郎伯旭 方震宇 [摘要] 目的 探討项八针联合吞咽康复训练对假性延髓麻痹吞咽障碍患者血清 VEGF、TGF-β1 的影响。 方法 选取 20XX 年 1 月～20XX 年 1 月本院收治的假性延髓麻痹吞咽障碍患者 136 例，依据不同治疗方法分为观察组和对比组，各 68 例，两组均行常规药物治疗，对比组在此基础上采纳项八针治疗，观察组采纳项八针联合吞咽康复训练治疗，比较两组患者治疗前后标准吞咽功能评估（SSA）评分、电视透视吞咽功能检查（VFSS）评分、血清血管内皮细胞生长因子（VEGF）、转化生长因子-β1（TGF-β1）水平的差异，并统计临床疗效。 结果 观察组和对比组治疗前的 SSA 评分、VFSS 评分、VEGF 和 TGF-β1 水平比较，差异无统计学意义（P>0.05）;治疗后，两组患者 SSA 评分较治疗前明显降低，VFSS 评分、VEFG、TGF-β1 水平较治疗前明显升高（P 结论 项八针联合吞咽康复训练能较好改善假性延髓麻痹吞咽障碍患者的吞咽功能，疗效优于单纯项八针治疗，其作用机制可能与调节血清 VEGF、TGF-β1 的代谢、促进血管生成、保护神经元有关。 [关键词] 项八针;吞咽康复训练;假性延髓麻痹;吞咽障碍;血管内皮细胞生长因子;转化生长因子-β1 [中图分类号] R246.6 [文献标识码] A [文章编号] 1673-9701（20XX）09-0007-04 [Abstract] Objective To explore the effect of cervical eight-needle combined with swallowing rehabilitation training on serum VEGF and TGF-β1 in patients with pseudobulbar paralysis dysphagia. Methods 136 patients with pseudobulbar paralysis dysphagia admitted 1下载后可任意编辑to our hospital from January 20XX to January 20XX were randomly divided into observation group and control group， 68 cases in each group. Both groups were given routine drug treatment. The control group was additionally given cervical eight-needle treatment，and the observation group was additionally given cervical eight-needle treatment combined with swallowing rehabilitation tr...