西药学专业 瑞舒伐他汀钙片药物临床应用及疗效

瑞舒伐他汀钙片药物临床应用及疗效摘 要目的：随着社会的发展，生活水平的不断提高，不良的生活习惯，高脂血症成为了现在中老年人的高发病症，并且逐渐年轻化，高脂血症是由于脂肪代谢异常引起血中总胆固醇/三酰甘油过高或高密度脂蛋白胆固醇过低所致血脂异常，高脂血症引起的动脉粥样硬化，从而导致高血压，冠心病，脑卒中，并且具有糖尿病密切相关，这些疾病均存在发病率高，危害大的特点，是威胁中老年人健康的主要原因，给社会和家庭带来了严重的思想负担和经济压力。方法：高脂血症的治疗主要还是依靠药物治疗，降血脂药物作为目前药物研发的活跃领域，已经取得了较为显著地成绩，本文将对瑞舒伐他汀钙片药物的应用状况做一综述。结果：有效的降低总胆固醇（TC）和低密度脂蛋白（LDL）降低三酰甘油（TG）结论：本品能适用于大多数患者，能相对安全的作用于无禁忌症的人群。关键词：瑞舒伐他汀钙片；降低总胆固醇；药物临床应用；疗效 Preparation and Studies on Indapamide Dropping PillsABSTRACTObjectives: Hypertension, a worldwide common disease，which is also have a great increase in CHINA,with the development of the living standard. As a desease of cardiovascular system, Hypertension is also a public health problem in global. Indapamide has been shown to be effective antihypertensive agents in patients with chronic renal failure. In china ,this kind of disease is not only highly occured among the old man aged over 60 years old ,but also can be easily found among the middle aged group.In this essay, It was used most frequently for the treatment of hypertension. In the present experiments, we prepared Indapamide dropping pills to increase its bioavailability and absorption. Methods: The matrix was PEG6000, the coolant was liquid paraffin and the instrument to make up dropping pills was artificial. Then through the orthogonal experiment of three influencing factors and three levels, taking spherical degree as index, we analyzed the effects of dropping distance, dropping r...