年产1.2亿颗氨苄西林胶囊（0.25g/颗）车间设计摘要：氨苄西林是广谱半合成青霉素，主要用于敏感菌所致的泌尿系统、呼吸系统、胆道、肠道感染以及脑膜炎、心内膜炎等。也用于伤寒、副伤寒；泌尿道、呼吸道感染。本文设计了年产1.2亿颗氨苄西林胶囊的车间,其主要内容包括生产工艺，生产工艺物料衡算，生产设备选型、车间平面布置设计，车间空调净化系统，胶囊剂GMP规范要求等。其原料来源广泛，成本低廉，生产工艺简单可靠，适合中小型企业生产。具有一定的设计意义。关键词:氨苄西林;胶囊;车间设计;物料衡算;设备选型Designworkshopofannualproductioncapacityof120millionampicillincapsule（0.25g/star）Abstract:Ampicillinisabroad-spectrumsemi-syntheticpenicillin,mainlyforthesensitivestrainscausedbytheurinarysystem,respiratory,biliary,intestinalinfections,andmeningitis,endocarditis,etc..Alsobeusedfortyphoidfever,paratyphoidfever;urinarytract,respiratorytractinfections.Thisarticledesignworkshopofannualproductioncapacityof120millionampicillincapsule.Itsmaincontentsincludetheproductionprocess,productionprocessmaterialbalance,productionequipmentselection,workshopslayoutdesign,workshopsairpurificationsystems,capsulesGMPrequirements.Itswiderangeofsourcesofrawmaterials,lowcostproductionprocessissimpleandreliable,suitablefortheproductionofsmallandmedium-sizedenterprises.Withacertainsenseofdesign.Keywords:Ampicillin;Capsule;Workshopdesign;Materialbalance;Equipmentselection目录前言............................................................................................................................1第一章设计指导思想和设计原则..............................................................................41.1指导思想..........................................................................................................41.2设计原则..........................................................................................................41.2.1厂区的选择和布置...............................................................................41.2.2工艺流程...............................................................................................41.2.3设备选型...............................................................................................51.2.4制剂车间的布置...................................................................................51.2.5空调净化系统.......................................................................................5第二章工艺流程设计................................................................................................62.1工艺规定..........................................................................................................62.2工艺设计参数..................................................................................................62.3工艺研究..........................................................................................................72.3.1工艺流程图...........................................................................................72.3.2工艺流程...............................................................................................7第三章物料衡算........................................................................................................143.1物料衡算........................................................................................................143.1.1生产能力..............................................................
