中国组织工程研究与临床康复第15卷第12期2011–03–19出版JournalofClinicalRehabilitativeTissueEngineeringResearchMarch19,2011Vol.15,No.12ISSN1673-8225CN21-1539/RCODEN:ZLKHAH2187DepartmentofNeurosurgery,AffiliatedHospitaltoGuilinMedicalCollege,Guilin541001,GuangxiZhuangAutonomousRegion,ChinaTangJing-feng★,Master,Associateprofessor,Associatechiefphysician,DepartmentofNeurosurgery,AffiliatedHospitaltoGuilinMedicalCollege,Guilin541001,GuangxiZhuangAutonomousRegion,Chinatangjingfeng152@163.comSupportedby:agrantbyHealthDepartmentofGuangxiZhuangAutonomousRegion,No.Z2008264*Received:2010-10-11Accepted:2010-11-30桂林医学院附属医院神经外科,广西壮族自治区桂林市541001唐景峰★,男,1975年生,广西壮族自治区灌阳县人,瑶族,1997年广西医科大学毕业,硕士,副教授,副主任医师,主要从事脑血管疾病和脑肿瘤的防治研究。tangjingfeng152@163.com中图分类号:R318文献标识码:B文章编号:1673-8225(2011)12-02187-05收稿日期:2010-10-11修回日期:2010-11-30(20101011008/W•Y)Onyx胶栓塞脑动静脉畸形31例*★唐景峰,黄永旺,杨保华,杜贻庆,莫万彬,阳永东,夏学巍,唐乐剑,周晓坤,王文波EmbolizationofcerebralarteriovenousmalformationwithOnyxin31casesTangJing-feng,HuangYong-wang,YangBao-hua,DuYi-qing,MoWan-bin,YangYong-dong,XiaXue-wei,TangLe-jian,ZhouXiao-kun,WangWen-boAbstractBACKGROUND:Asfortheendovascularembolizationtreatmentofcerebralarteriovenousmalformations,theembolicmaterialsplayagreatlydecisiveroleonthetherapeuticeffect.Onyxisanewliquidembolicagentdevelopedinrecentyears,withnon-sticktube,dispersionuniformityandgoodcontrollability.OBJECTIVE:Tosummarizetheembolizationtechniquesandclinicalefficacyofcerebralarteriovenousmalformationbyusinganewliquidembolicagent(Onyx).METHODS:Thirty-onepatientswithcerebralarteriovenousmalformationweretreatedwithOnyx,6FsheathinsertedintofemoralarteryusingSeldingertechniquefollowedby6Fguidingcatheterintroducedintotheinternalcarotidarteryorvertebralartery,Marathonmicro-cathetercouldbenavigatedintothenidusofarteriovenousmalformation,thentheOnyxwasinjectedslowlyintothecerebralarteriovenousmalformationwith“inject-backflow-stop-reinject”technique.RESULTSANDCONCLUSION:40%-60%embolizationswereachievedin8cases,60%-90%in7cases,morethan90%(completeembolization)in16cases.Among15casesofincompleteembolization,4underwentsurgicalremovalincluding3caseswithgoodoutcomeand1caseofhemiplegiawithmuscularstrengthofdegreeⅣ;6casesweretreatedbyγ-knifeafterembolization,2casesofthemshowedcompleteocclusionafterradiosurgery.Onyxhasuniqueanddistinctivesuperiorityintreatingcerebralarteriovenousmalformations.However,theembolizationtechniquesshouldbewelltrainedtogetgoodresultsandavoidcomplications.TangJF,HuangYW,YangBH,DuYQ,MoWB,YangYD,XiaXW,TangLJ,ZhouXK,WangWB.EmbolizationofcerebralarteriovenousmalformationwithOnyxin31cases.ZhongguoZuzhiGongchengYanjiuyuLinchuangKangfu.2011;15(12):2187-2191.[http://www.crter.cnhttp://en.zglckf.com]摘要背景:在脑动静脉畸形的血管内栓塞治疗中,栓塞材料的选用在很大程度上决定血管内栓塞治疗的效果。Onyx胶是近年研制的一种新型液体栓塞剂,具有不粘管、弥散均匀及可控性好等优点。目的:总结新型液态栓塞剂Onyx胶栓塞脑动静脉畸形31例的技术要点和临床疗效。方法:应用Onyx胶栓塞脑动静脉畸形31例,均采用Seldinger技术在股动脉内置入6F动脉鞘,6F导引导管插入颈内动脉或椎动脉,Marathon微导管超选择进入畸形血管团内,采用“注胶-返流-停止-再注胶”技术长时间缓慢注射Onyx胶栓塞脑动静脉畸形。结果与结论:栓塞后脑动...