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11stChineseLipoidConference第一届Lipoid中国研讨会PhospholipidsforAdvancedDrugDelivery磷脂对于给药系统的完善Shanghai,June21st2007上海，2007.6.212Agenda议程安排09:00Registration登记签到09:30AddressofwelcomefromLipoidandintroductionoftheLipoidGroupLipoid致欢迎词及Lipoid简介09:45AddressofwelcomefromthePhospholipidResearchCenter磷脂研究中心致欢迎词10:00PhospholipidsinparenteralsystemsI注射用磷脂13Agenda议程安排10:45CoffeeBreak议间休息11:00PhospholipidsinparenteralsystemsII注射用磷脂212:00Lunch午餐13:00Phospholipidsintopicalandoralsystems磷脂在外用及口服系统中的运用14:00CoffeeBreak议间休息14:15Regulatoryandsafetyaspects规定及安全方面15:15Closing结束4TheCompanyTheCompany公司简介�Founded1977成立于1977�Holding控股LipoidVerwaltungsGmbH�Affiliates分支LipoidGmbH,LudwigshafenLipoidAG,SwitzerlandLipoidLLC,USAALC,USAR&RExtrakte,KölnPhospholipidGmbH,Köln5TheLIPOIDGroupLIPOID集团Production工厂PhospholipidGmbHGermanyPhospholipid工厂（德国）LipoidGmbHGermany利宝益工厂（德国）R&RExtrakteGmbHGermanyR&R工厂（德国）6TheLIPOIDGroupLIPOID集团Marketing销售AmericanLecithinCompanyConnecticutALC公司(康涅狄格)PhospholipidGmbHGermanyPhospholipid(德国)LipoidLLCNewJersey利宝益LLC（新泽西）LipoidAGSwitzerland利宝益(瑞士)7TheCompanyTheCompany公司简介�LipoidGmbH,Ludwigshafen利宝益工厂，位于路德维希港�Productionofphospholipids磷脂的生产环境8TheCompanyTheCompany公司简介�R&RExtrakte,KölnR&R公司�Productionofplantextract植物提取物的生产�Secondproductionsiteofphospholipids磷脂生产基地9TheCompanyTheCompany公司简介�LipoidLLC,USA利宝益美国�ALC,USAALC美国�LipoidAG,Switzerland利宝益瑞士�Technicalsupportandsales技术支持与销售业务10TheCompany公司简介�PhospholipidGmbH,KölnPhospholipid公司�Developmentandproductionofsoyphospholipids进行大豆磷脂的深加工和生产�Salesandtechnicalsupportworldwide,exceptUSAandCanada提供全球（不包括美国和加拿大）技术支持及销售业务11TheCompany公司简介-NaturalPLfromeggandsoya天然的蛋黄和大豆磷脂-HydrogenatedPLfromeggandsoya氢化蛋黄和大豆磷脂-SyntheticPL合成磷脂-Tailoredlipidblends磷脂混合物CoreBusiness业务核心�Phospholipidsforpharmaceuticalapplications磷脂在医药行业的应用�Highlypurifiedoils精制油类-Soybeanoil大豆油-Oliveoil橄榄油-MCT中链甘油三酸酯-Fishoil鱼油12TheCompany公司简介�Manufacturinginindustrialscale工业化大生产Focus主营�Developmentofnewphospholipidsandrelatedsubstances开发新的磷脂和相关产品13TheCompany公司简介�Manufacturingprocessesdevelopedandvalidatedbyourselves自行改进和检验生产工艺�Productsforparenteralusefilteredthrough0.2µmintoacleanroomclassISO5(=class100)注射用产品需通过0.2µm过滤进入ISO5的净室�Dryingandpackagingunderasepticconditions在无菌环境下干燥和包装Technology技术14TheCompany公司简介QualitySystem质量体系�cGMP�CertifiedaccordingtoICHQ7A�ISO9001�DrugMasterFiles15Products产品�Pharmaceutical(>80%)药用客户（占80%）�Cosmetic化妆品�Dietetic保健品行业Customers目标客户PharmaceuticalApplication药用方面�Mainlyforparenteraluse(>90%)主要供注射用-Fatemulsions脂肪乳-Liposomes脂质体-Mixedmicelles混合胶束16DefinitionofLecithin卵磷脂的定义USP:“Lecithinisacomplexmixtureofacetone-insolublephosphatides,whichconsistchieflyofphosphatidylcholine,phosphatidylethanolamine,phosphatidylserineandphosphatidylinositol,combinedwithvariousamountsofothersubstancessuchastriglycerides,fattyacidsandcarbohydrates,asseperatedfromthecrudevegetableoilsource.Itcontainsnotlesstha...