精品文档---下载后可任意编辑β-取代-α，γ 二氨基酸与含多手性中心的吡咯烷衍生物的不对称合成的开题报告摘要：本文介绍了一种合成 β-取代-α，γ 二氨基酸和含多手性中心的吡咯烷衍生物的不对称合成方法。该方法利用手性催化剂作为催化剂，通过惠普地震反应在不对称条件下控制了反应的立体选择性，得到了高收率和高对映选择性的产物。本讨论为合成天然产物及其类似分子提供了新思路，具有一定的理论和实践意义。关键词： β-取代-α，γ 二氨基酸；吡咯烷衍生物；不对称合成Abstract:This paper describes an asymmetric synthetic method for synthesizing β-substituted α,γ-diamino acids and polycyclic pyrrolidine derivatives with multiple stereocenters. The chiral catalyst is used as a catalyst, and the stereo-selectivity of the reaction is controlled under asymmetric conditions through the HWE reaction, resulting in high yields and high enantiomeric selectivity. This research provides a new way to synthesize natural products and similar molecules, and has certain theoretical and practical significance.Keywords: β-substituted α,γ-diamino acids; pyrrolidine derivatives; asymmetric synthesis
