精品文档---下载后可任意编辑风心病患者二尖瓣口面积及心脏结构十九年变化趋势分析的开题报告AbstractBackground: Rheumatic heart disease (RHD) is a significant cause of morbidity and mortality worldwide. Patients with RHD are at risk of developing severe mitral valve disease, including mitral stenosis (MS), which can lead to significant hemodynamic compromise. Echocardiographic assessment of the mitral valve is crucial in the diagnosis and follow-up of RHD.Objectives: The main objective of this study is to evaluate the changes in the mitral valve area and cardiac structure of RHD patients with MS over a 19-year period.Methods: This retrospective analysis will include patients diagnosed with RHD with MS between 2024 and 2024 at the Shandong Provincial Hospital in China. Their medical records and echocardiographic data will be reviewed to extract information on mitral valve area (MVA), left atrial (LA) and left ventricular (LV) dimensions, ejection fraction (EF), and pulmonary artery pressure (PAP). The data will be analyzed by comparing the baseline and follow-up echocardiographic measurements.Results: The results of this study will be presented as baseline characteristics, change in mitral valve area, and changes in cardiac structure over the follow-up period. A repeated measures analysis of variance will be performed to determine the changes in echocardiographic parameters over time.Conclusions: This study will provide insight into the natural history of MS in RHD patients and will help identify factors that contribute to changes in the mitral valve area and cardiac structure over time. The results of this study may guide management strategies for RHD patients with MS. Keywords: Rheumatic heart disease, mitral stenosis, echocardiography, cardiac structure, China
