精品文档---下载后可任意编辑鼻咽癌 IMRT 靶区勾画中不同影像学检查的比较及近期疗效观察的开题报告摘要：目的：讨论不同影像学检查在鼻咽癌 IMRT 靶区勾画中的适用性，并对近期疗效进行观察。方法：选择 50 例鼻咽癌患者进行讨论，分别采纳 CT、MRI、PET-CT 进行靶区勾画，比较不同影像学检查在勾画中的差异性。进行 IMRT治疗后观察患者治疗期间的疗效及 3 个月后的疗效情况。结果：50 例患者中，使用 MRI 勾画的靶区面积最大，使用 PET-CT勾画的靶区面积最小；使用 CT 勾画的靶区与 MRI、PET-CT 存在显著差异（P<0.05）。采纳 IMRT 治疗后，45 例患者得到了完全缓解，5 例患者得到了部分缓解。3 个月后的随访结果显示，50 例患者中没有出现复发或转移。结论：在鼻咽癌 IMRT 靶区勾画中，MRI 具有较高的适用性，PET-CT 可以辅助 MRI 进行勾画。IMRT 治疗方案可以达到较好的疗效，且疗效持久。关键词：鼻咽癌；IMRT；勾画；影像学检查；疗效观察Abstract:Objective: To investigate the applicability of different imaging examinations in the delineation of nasopharyngeal carcinoma (NPC) IMRT target area and observe the recent therapeutic effect.Methods: Fifty patients with nasopharyngeal carcinoma were selected for the study, and CT, MRI, and PET-CT were used to delineate the target area. The differences in delineation by different imaging examinations were compared. The therapeutic effect during the treatment and 3 months after the treatment was observed.Results: Among the 50 patients, the target area delineated by MRI was the largest, and the target area delineated by PET-CT was the smallest. There were significant differences in the target area delineated by CT compared with that by MRI and PET-CT (P<0.05). After IMRT treatment, 45 patients achieved complete remission, and five patients achieved partial 精品文档---下载后可任意编辑remission. Three months later, none of the 50 patients had recurrence or metastasis.Conclusion: MRI has a higher applicability in the delineation of NPC IMRT target area, and PET-CT can assist MRI in delineation. The IMRT treatment scheme can achieve good therapeutic effect and last for a long time.Keywords: Nasopharyngeal carcinoma; IMRT; delineation; imaging examination; therapeutic effect observation.
