介孔材料分子印迹聚合物的制备及固相萃取

介孔材料分子印迹聚合物的制备及固相萃取 摘 要在本文中,我们制备的提取青蒿素的分离和纯化(ARS),这是传统的中国医药青蒿 Artemizinin 用作模板分子的活性组分分子压花聚合物(MIP)的基础上,包装在固相偶氮二异丁腈(广告被用于来完成。用于分子压花聚合物 ARS 使用 KH550(APTES 进行表面压花的制备)改性的中孔材料(AP-MCM41)作为载体作为引发剂。介孔材料和聚合物,其分子量压花 artemizinini 已经确定通过红外光谱与傅里叶变换,物理吸附,和透射电子显微镜。结果表明,该分子印迹聚合物 ADR 在最佳制备 p ONDITIONS 吸附容量是 102.25 毫克/克,这比在 neimprintiranih 聚合物显著更高。选择性实验 artemizinina,双氢和蒿甲醚具有 MIP 更高的选择性为 artemizinin 和其结构类似物如 artemizinina 印迹聚合物,通过常规方法制备。性别。定义也确定了选择性和所提取的提取物青蒿 97,98%RSD 和小于 1.78%的平均产率。并提供青蒿素的分离和提纯的新方法。关键词：青蒿素；分子印迹聚合物；固相萃取；介孔材料IAbstractIn this paper, we prepared the extraction and purification of artemisinin (ARS), which is based on the traditional Chinese medicine Artemisinin used as a template molecule for the active component of molecular embossed polymer (MIP), packaged in Solid phase, azobisisobutyronitrile (advertising was used to complete. The molecular embossed polymer ARS uses KH550(APTES for surface embossing preparation) modified mesoporous material (AP-MCM41) as a carrier as an initiator. Mesoporous materials and polymers, whose molecular weight embossing artemizinini has been determined Infrared spectroscopy with Fourier transform, physical adsorption, and transmission electron microscopy. The results show that the molecularly imprinted polymer ADR in the optimal preparation of p ONDITIONS adsorption capacity artemizinina is 102. The selective experiment artemizinina, dihydrogen and artemether have a higher selectivity for MIP for artemizinin and its structural analogues such as artemizinina impr...