国外骨折风险评估工具FRAX的应用进展VIP专享

国外骨折风险评估工具 FRAX 的应用进展摘要：骨质疏松性骨折是骨质疏松最严重的后果，世界卫生组织推举使用简单易行的骨折风险预测工具 FRAX 评估患者的骨折风险，针对高风险人群进行及时干预，大大降低其危害。国外有关 FRAX应用讨论逐渐精细和深化，有关 FRAX 在不同疾病患者中的适用性，及结合、不结合股骨颈 BMD 对 FRAX 预测结果影响的讨论逐渐增多。本文就 FRAX 在国外类风湿关节炎、绝经后女性和糖尿病患者中的应用现状进行综述，FRAX 在不同病种的应用为临床医生及护士积极实行防治及护理措施提供决策和依据。关键词：骨质疏松性骨折；骨折风险性；风险因子；FRAXApplication progress of fracture risk assessment tool FRAX in foreign countriesLIU SuxiangThe Fourth Affiliated Hospital of Zhejiang University Medical CollegeAbstract: Osteoporotic fracture is the most serious consequence of osteoporosis, the World Health Organization recommends the use of simple fracture risk prediction tools FRAX, timely intervention for high-risk groups can greatly reduce the harm. In foreign countries, the application study of FRAX gradually elaborate and in-depth, the study of FRAX scores calculated with or without femoral neck bone mineral density gradually increase. This article reviews the application status of FRAX in rheumatoid arthritis, postmenopausal women and patients with diabetes mellitus. FRAX applications in different kinds of disease provide decision-making and basis for clinical doctors and nurses to take active measures.Key words: Osteoporotic fracture; Fracture risk; Risk factors; FRAX 骨质疏松（osteoporosis，OP）是以骨量减少、骨的微观结构退化为特征的，致使骨的脆性增加以及易于发生骨折的全身性骨骼疾病 [1]。发生骨质疏松性骨折（osteoporosis fracture，OF）是 OP 最严重的后果，其具有高发病率、高死亡率的特点[2]，有讨论估计到 2025 年欧洲人群之中每年发生 OF 的次数可达 450 万次[3]，由 OF 产生的直接费用在美国为 190 亿美元[4]，由此产生的治疗和护理费用给家人及社会...