•Definitionofhepaticencephalopathy•Clinicalpresentationsofhepatic•Diagnosisanddifferentialdiagnosisofhepaticencephalopathy•Treatmentandnursingofhepatic•PreventionanddiagnosisofhepaticCHAPTERWhatishepaticencephalopathyHepaticencephalopathy(HE)isaneurologicalconditionthatoccursasaresultoflivefailureorportalsystemshutdownItischaracterizedbyaspectrumofsymptomsrangingfrommillcognitiveimpairmenttocomaHEiscausedbytheaccumulationofammoniaandothertoxinsinthebrain,leadingtoneuroimagingandoxidativestressClassificationofhepaticencephalopathyHEisclassifiedaseitherovertorcoverOverHEismanifestbysymptomssuchasfusion,differentiation,andcoma,whilecoveringHEischaracterizedbysubneopsychiatricchangeslikepersonalitychangesandpsychomotorretentionPathogenesofhepaticencephalopathyPathogenesofhepaticencephalopathy输