CornealdiseaseCornealdiseaseGeneral•Functions1.corneaandscleramakeuptheexternalwall2.importantrefractionsubstance:+43D，3/4ofthetotalrefractivepower3.nobloodvesselImmuneprivilegeTransparentcorneaEpitheliumBasalcellsBowmanmembraneStromaDescemetmembraneEndotheliumKeratitis•Etiology1.infectivity:bacteria、fungi、virus、acanthaamoeba2.endogenetic:3.spread:PathobiologyPathobiology•causativeagentinfiltrationtransparentcornealulcerdescemetocelecornealperforationnebulamaculacornealscarcornealfistulaleucomaAdhesivenesskeratoleukomaglaucomacornealstaphylomapanophthalmitisatrophiabulbi（眼球萎缩）clinicalmanifestation•Symptom:ophthalmalgia、photophobia、tearing、spasmofeyelid、secretion、sightdescent•Sign:ciliarycongestion、cornealinfiltration、cornealulcerDiagnose•Symptom+Sign•laboratoryexaminationTherapy•Removeetiologicalfactor•Controlinfection•Promotehealing•DecreasecicatricleBacterialkeratitis•Etiologycornealtraumapathogenicbacteriapartly&systemicfactors
