2025年早期血浆置换治疗高脂血症性急性胰腺炎的临床意义VIP免费

早期血浆置换治疗高脂血症性急性胰腺炎的临床意义 目的 探讨早期血浆置换（plasma exchange，PE）对高脂血症性急性胰腺炎（acute hyperlipidemic pancreatitis，HLP）的治疗作用。 办法 将 42 例 HLP 患者随机分为两组，治疗组 22 例（常规治疗＋早期 PE），对照组 20 例采用常规治疗。比较 PE 两组患者血清甘油三酯（TG）浓度、急性生理和慢性健康评价指标Ⅱ（APACHE Ⅱ）评分、C-反映蛋白（CRP）浓度变化，并观察两组患者的临床体现和预后。 成果 入院 24 h，两组患者血清 TG 浓度较入院时均减少，且治疗组血清 TG 浓度明显低于对照组（ P＜0.01）；入院 48 h，治疗组APACHE Ⅱ 评分、CRP 浓度均低于对照组（P=0.032；P=0.017）；治疗组患者腹痛、腹胀缓和时间，禁食水时间，住院时间均较对照组缩短（P＜0.01）；治疗组及对照组的病死率分别为 9.1%、25.0%，两者比较差别无统计学意义（P=0.333）。 结论 早期 PE 可明显减少患者血清 TG 浓度，改善患者的临床症状，是治疗 HLP 的安全、有效的手段之一。 标签： 高脂血症性急性胰腺炎； 血浆置换； 甘油三酯 The clinical effects of the earlier plasma exchange in the treatment of hyperlipidemic acute pancreatitis ZHOU Ming-yin ， CHEN Tao ， WANG Yong-guang.The Central Hospital of XinYang，XinYang 464000，China 【Abstract】 Objective To evaluate the effect of earlier plasma exchange in the treatment of patients with The hyperlipidemic acute panercatitis （HLP）. Methods 42 patients with HLP were divided into 2 groups: the treatment group（22cases）was given the conventional therapy and the plasma exchange ； the control group（20 cases）was given the only conventional therapy. and then The triglyceride levels in serum、the sorces of acute physiology and chronic health evaluation Ⅱ as well as the C-reactive protein levels in serum were compared before and after the plasma exchange respectively. their clinical features and prognosis were also observed. Results After 24 hours in hospital ， triglyceride serum leve...