下载后可任意编辑利培酮与氯氮平对精神分裂症患者生存质量影响的比较讨论:利培酮和氯氮平的区别利培酮与氯氮平对精神分裂症患者生存质量影响的比较讨论:利培酮和氯氮平的区别 [摘要] 目的:比较利培酮与氯氮平对精神分裂症患者生存质量的影响。方法:采纳阳性与阴性症状量表(PANSS),副作用量表(TESS),健康状况问卷(SF-36)进行疗效、副作用和生存质量评估,并对影响生存质量的某些因素进行多元逐步回归分析。结果:两组 PANSS 评分治疗前[(71.7±17.50),(66.03±14.13)]、治疗后[(41.27±9.39),(38.93±7.68)]比较,均有显著性差异(P<0.01),而两组同期相互比较,则无显著性差异。治疗结束后,利培酮组生理功能、生理职能、生命活力、社会功能、情感职能4个因子分及生存质量总评分均明显高于氯氮平组,且治疗前后评分有显著性差异。多因素逐步回归分析显示,影响患者生存质量的主要因素依次为精神症状、药物、副作用、病程。结论:利培酮与氯氮平对精神分裂症疗效相当,生存质量优于氯氮平。 [关键词] 利培酮;氯氮平;精神分裂症;生存质量 [ 中 图 分 类 号 ] R971+.4[ 文 献 标 识 码 ]C [ 文 章 编 号 ]1673-7210(20XX)11(c)-050-0 3 Comparative study on the effects of Risperidone and Clozapine on the quality of life in patients with schizophrenia ZHOU Zi-jun, XIA Ke-zhi, YANG Kai-yan, XU Xiao-ming, LI Song (The Psychology Health Section , Liaoning Province Iron Coal Group General Hospital,Tielingxxxx,China) [Abstract] Objective: To compare the effects of Risperidone and Clozapine on the quality of life in patients with schizophrenia. 1下载后可任意编辑Methods : Used of positive and negative symptoms Scale (PANSS) , Vice-Scale (TESS) , health status questionnaire (SF-36) for efficacy, side effects and quality of life assessment and impacted on quality of life for some of multiple factors regression analysis. Results: PANSS score of two groups before treatment[(71.7±17.50),(66.03±14.13)]and after treatment[(41.27±9.39),(38.93±7.68)] all had significantly different (...