Claudia Schäfer, Global Customer Support, Penzberg 4486 MODULAR ANALYTICS E170, cobas e 601, cobas e 602, Elecsys® 2010, cobas e 411 Elecsys® Dilution Recommendations Autodilution possible for bold mentioned dilution ratios Dilution not necessary due to the broad measuring range or not possible e.g. can not be diluted because of changing in the concentration of the binding proteins alters this equilibrium. @ The autoantibodies are heterogeneous and this gives rise to non-linear dilution phenomena. * Please check the package insert. STAT for Elecsys 2010, cobas e 411, cobas e 601 (SW version 04-03 onwards) and cobas e 602 # Diluent Universal can be used to dilute the samples. Auto-dilution is not possible as assay uses a three-step method. Use Elecsys® Diluent Universal for automatic sample predilution. Autodilution not possible. Diluent ratio Version 4.6 May 2011 1/7 Reagent type Test Recommended dilution ratios Concentration of diluted sample must be Thyroid Function Test FT3 FT4 T3 T4 TSH 1:10 with Diluent MA > 10 µIU/ml T-uptake TG 1:5 with Diluent Universal > 50 ng/ml Anti-TG @ Anti-TPO @ 1:5 with Diluent Universal manually > 100 IU/ml Anti-TSHR 1:5 or 1:10 with Anti-TSHR negative human sera* > 4 IU/l Cardiac CK-MB (STAT) 1:2 with Diluent MA > 50 ng/ml Digoxin 1:2 with Diluent Universal > 2.5 ng/ml >3.2 nmol/l Digitoxin 1:2 with Diluent Universal > 30 ng/ml > 39 nmol/l Myoglobin (STAT) 1:10 with Diluent Universal > 50 ng/ml proBNP II (STAT only cobas e 601/2) 1:2 with Diluent Universal > 15000 pg/ml > 1770 pmol/l Troponin I (STAT) 1:10 with Diluent MA > 3 µg/l > 3 ng/ml Troponin T (STAT) 1:10 with Diluent Universal > 1 µg/l > 1 ng/ml Tropo...
