精品文档---下载后可任意编辑HCY、MMP--9TIMP--1 失衡与颈动脉粥样硬化斑块稳定性的关系的开题报告摘要：颈动脉粥样硬化斑块的稳定性是指斑块的倾向于破裂造成栓塞或血管狭窄，是其病理特征的关键之一。HCY、MMP-9、TIMP-1 是三种分别由半胱氨酸、基质金属蛋白酶-9、组织抑制金属蛋白酶-1（TIMP-1）所表达的蛋白，与颈动脉粥样硬化及斑块稳定性密切相关。因此，本文将综述 HCY、MMP-9、TIMP-1 失衡与颈动脉粥样硬化斑块稳定性的关系，并探讨其病理生理机制，为早期干预和治疗提供相关的理论依据。关键词：颈动脉粥样硬化斑块稳定性，HCY，MMP-9，TIMP-1，失衡Abstract:The stability of carotid atherosclerotic plaques refers to the tendency of plaques to rupture and cause thromboembolism or vascular stenosis, which is one of the key pathological features. HCY, MMP-9, and TIMP-1 are three proteins expressed by homocysteine, matrix metalloproteinase-9, and tissue inhibitory metalloproteinase-1 (TIMP-1), which are closely related to carotid atherosclerosis and plaque stability. Therefore, this article will review the relationship between the imbalance of HCY, MMP-9, and TIMP-1 and the stability of carotid atherosclerotic plaques, and explore its pathological and physiological mechanisms to provide relevant theoretical basis for early intervention and treatment.Keywords: stability of carotid atherosclerotic plaques, HCY, MMP-9, TIMP-1, imbalance
