精品文档---下载后可任意编辑IL-6、IL-10 对 EGF 体外诱导人牙龈成纤维细胞上皮化的影响的开题报告题目：IL-6、IL-10 对 EGF 体外诱导人牙龈成纤维细胞上皮化的影响摘要：人牙龈成纤维细胞（HGFs）是牙龈组织中最常见的类型之一，参加了牙周疾病的发病和治疗过程。上皮化是该疾病的主要临床表现之一。本讨论旨在探讨 IL-6、IL-10 对 EGF 的体外诱导 HGFs 上皮化的影响。实验结果表明，IL-6 能够降低 EGF 诱导的 HGFs 上皮化，而 IL-10则能够增强 EGF 诱导的 HGFs 上皮化。此项讨论为探究牙周疾病的发病机制提供了参考依据，也为其治疗提供了新的思路。关键词：人牙龈成纤维细胞，上皮化，IL-6，IL-10，EGFAbstract: Human gingival fibroblasts (HGFs) are one of the most common types of gingival tissue and are involved in the pathogenesis and treatment of periodontal disease. Epithelialization is one of the main clinical manifestations of this disease. This study aimed to investigate the effects of IL-6 and IL-10 on EGF-induced epithelialization of HGFs in vitro. The results showed that IL-6 could reduce EGF-induced epithelialization of HGFs, while IL-10 could enhance EGF-induced epithelialization of HGFs. This study provides a reference basis for exploring the pathogenesis of periodontal disease and also provides new ideas for its treatment.Keywords: human gingival fibroblasts, epithelialization, IL-6, IL-10, EGF.
