毕 业 设 计（论文）2024 届题 目 穿心莲酯的提取工艺讨论 专 业制药工程学生方梅芬 学 号 0 8 0923 12 指导老师 莉 论文字数 10319 字 完成日期 2024 年 5 月 湖 州 师 学 院 教 务 处 印 制穿心莲酯的提取工艺讨论08092312 方梅芬(师学院生命科学学院， 313000)摘要： 在单因素试验的基础上，采纳正交试验法优选穿心莲酯超声波提取法最佳提取条件。以穿心莲茎干粉末为原料，改变超声振荡功率、时间、料液比、不同溶剂、反应温度等单因素变量，提取液经配制后测量吸光度值，选定三水平后进行正交试验。以穿心莲酯对比品制备标准液，计算回归方程为：Y=13.7828x-0.0074，R2=0.9692。结果表明，超声波提取的最佳工艺条件为：在 60℃下，以乙酸乙酯为溶剂，料液比为 1:30，功率为 140w，超声提取 60min，测得穿心莲提取液的吸光度为 0.951。关键词：穿心莲酯; 超声波; 提取Extraction Process of Andrographolide08092312FANG Meifen（School of Life Science，Huzhou Teachers College，Huzhou 313000 ）Abstract:On the basis of one-factor experiment, orthogonal experiment method was employed for the optimization of ultrasonic extraction of Andrographis paniculta lactone. To stem powder andrographis as raw materials, change the single factor variables of ultrasonic oscillator power, the oscillator time, the solid-liquid ratio,the different solvent and the reaction temperature,extrat after configurationmeasuring absorbance, and then selected three levels before orthogonalexperiment.With andrographis paniculta lactone reference substancepreparation standard fluid, calculate a regression equation for: Y = 13.78281 x -0.0074 R2 = 0.9692.The optimum conditions of ultrasonic extraction of Andrographis paniculta lactone as follows: in 60 ℃,use ethyl acetate, the solid-liquid ratiois 1:30, ultrasonic oscillator power is 140 w, and ultrasonic extraction 60 min.measuring absorbanceAndrographis panicultaextrat is 0.951.Keywords: andrographis paniculta lactone; Ultrasonic; Extracte...
