分类号：单位代码：84502密级：学号：中国中医科学院临床医学专业博士学位论文强骨灵胶囊治疗原发性骨质疏松症肾元亏虚型的临床研究申请人：程伟专业：中西医结合临床研究方向：老年病研究导师：周文泉主任医师中国中医科学院西苑医院2008年5月北京目录中文摘要............................................................1ABSTRACT............................................................5缩略词表............................................................9文献综述...........................................................11综述一骨质疏松症的中医药研究进展...............................11综述二骨质疏松症的药物治疗研究.................................25前言............................................................35临床研究...........................................................371.资料与方法....................................................371.1诊断标准....................................................................................................371.2病例选择....................................................................................................381.3一般资料....................................................................................................391.4治疗用药及疗效观察方法........................................................................391.5观测指标及方法........................................................................................401.6疗效判定....................................................................................................421.7知情同意书................................................................................................421.8统计处理....................................................................................................432.结果..........................................................432.1临床疗效比较............................................................................................432.2中医证候疗效比较....................................................................................442.3单项症状改善比较....................................................................................452.4病情分级疗效比较....................................................................................472.5骨密度疗效观察........................................................................................482.6骨代谢指标观察........................................................................................482.7雌激素水平观察........................................................................................512.8脱落病例情况............................................................................................512.9安全性指标及药物不良反应观察............................................................513.讨论..........................................................51I3.1骨质疏松的病因病机及理法方药的确立................................................513.2强骨灵胶囊方解........................................................................................523.3强骨灵胶囊的临床疗效分析....................................................................533.4强骨灵胶囊对骨密度影响........................................................................543.5强骨灵胶囊对骨代谢指标的影响............................................................553.6强骨灵胶囊对雌激素的影响....................
