百度文库-让每个人平等地提升自我1、局部麻醉剂苯佐卡因的合成：CH3HNO3/H2SO4CH3KMnO4NO2ABCO2HH2/Pd/CCO2HEtOH/H3O+CO2EtNO2CNH2DNH2E目标分子2、H3CH3CCOCNNaCNH3CCdil.H2SO4HCHO3MeOHH2SO4TM23、CH3COCl/AlCl3COCH3(1)EtMgBr(2)H3O+TM34、OClAlCl3OHCHONON(1)(2)H3O+MgBrTM4OCO2H(1)SOCl2(2)C6H6TM4N(1)OClNMg/EtO2NMgCl(2)PCl51百度文库-让每个人平等地提升自我5、OH3CCCH3(1)NaCN(2)H+CH3H3CCOHCNCH3H3CCOH6、OHCCHNaNH2CNTM5(1)PhCCH3HCCNa(2)H3O+PhCH3COHCCHPhCH3COHCCHTM67、PhOHTM7OCH3COClAlCl3(1)CH3CH2CH2MgBr(2)H3O+PhOH8、OaOHbTM8ab+MeMgXMgBr+CH3COCH39、a.+CO2Etb.+CHOCHO(1)LiAlH4CO2Et(2)H3O+TM9(1)NaBH4(2)H3O+TM9OHTM9ORMgX+CH3OCOCH3(1)Et2O(2)H3O+RRCROH10、2百度文库-让每个人平等地提升自我aaOHPhTM10bbPhPhPhCO2EtCO2HCH2OHPhMgBr+O+2MeMgBr11、RCO3HO(1)PhMgX(2)H3O+TM11OHRCH2OHRR'R'CHOOHR'RR''HCHOR'COR''RMgXOR'HCO2EtRCHOH2R'CO2EtOHRR'RXR'MgOR'CHCH2ROHRCH2CH2OHHCCMgBrBrMgCCMgBr(1)COHCH(2)H3O+OCH3CHgBr2CH2M2CH3CH2MgBr(1)OHCCHNaNH2CCOHNaNH2(2)H3O+OHHCCNaNaCCNa12、OAcPhPhTM123百度文库-让每个人平等地提升自我(1)Mg,Et2OBr(2)HCO2EtPh(3)H3O+OHPhAc2OPhTM1213、OTM13(1)Mg,Et2OBr(2)HCHO(3)HO+3OH[O]O(1)H(2)H3O+MgBrOH[O]TM1314、ClO2NTM14HCHO/HClZnCl2OHO2NSOCl2CH2ClHNO3Ac2OO2NCH2Cl(1)Mg,EtO2(2)CH3COCH3(3)H3O+TM1415、H3CH3CCH2PhabTM15H3CH3CH3CH3COHH3PO4CH2PhOHCH2PhAH3CH3CO+PhCH2CH2BrCH2PhPhCH2CH2Br(1)Mg,Et2OH3C(2)CH3COCH3H3COH+(3)H3OTM154百度文库-让每个人平等地提升自我16、CO2Et(1)4PhMgBrTM16+CO2Et(2)H3OPhOHOHCO2EtCO2EtB+4PhMgBrPhPhOPhPhTM16PhPhAPh17、aaOHbPhbTM17MgBr+HOH+BrMgOPhPhOHBr+HCHO18、OONaNH2/HCHONaNH2/HCHOHOHOTM18H2/Pd/H2SO4HOHOOTM18DryHClHCCH19、MgBr+CH3CO2EtOHMgBrHOHO20、5Ph+O百度文库-让每个人平等地提升自我OOHPh21、(1)PhMgBr(2)H3O+H3PO4TM20MeI+Ph3PH3CPPh3+(1)CH3CH2CH2CH2LiO(2)TM21abO++H3CPPh3HCHO+Ph3P+22、如何制备TM22PhCHOCHO+PhCH2CH2Br+PPh3PhCH2CH2PPh3(2)PhPh+(1)CH3CH2CH2CH2LiCHOTM2223、试设计TM23的合成路线。Ph3P+BrCH2CH2CH2CH2BrPh3PCHCH2CH2CH2Br+-Ph3PCH2CH2CH2CH2BrHPh3P+PhLiPhPh+PhLiPh3POTM2324、炔烃的还原6百度文库-让每个人平等地提升自我H2/Pd/BaSO4RCCR'NaNH3(l)RRR'R'由小于或等于C2的有机化合物合成HCH3CH2HCH2CH3TM24CH3CH2CCCH2CH3HCCH2NaNH2NaCHCNaCH3CH2Br2HCH2CH3H2/Pd/BaSO425、如何制备下列化合物CH3CH2OOOTM25[合成]邻苯二酚是易得的原料。OHOHCHOOClTM25OHODryHClAlCl326、[分析]7OMeOMeNO2bMeNO2TM26OMeOMeaOMeMeCl+OMeOCl+ONO2NO2百度文库-让每个人平等地提升自我27、[分析][合成]OHCH3C6H5SO2Cl/NaOHCH3KMnO4OSO2C6H5CO2HH+OSO2C6H5OHCO2HCH3CO2HO试设计PhTM27的合成路线PhOHOOHPhPhOCO2Et+2PhMgBrOO1.2PhMgBrCO2Et2.H+/HO2TM27例1．实现CHO的转化。CHOBrBrCH(OEt)2dil.HClCH(OEt)2CHOCHOKOH/EtOH2EtOHH+CH(OEt)2Br2例2．试实现下列转换：OHOH8百度文库-让每个人平等地提升自我例3．试实现下列转化。28、[合成]29、[合成]30、[合成]OCO2Et1.NaOEt2.CH3I1.NaOEtBr2.OCO2Et1.NaOH/H2O2.H3O+3.heatOBrCHOCHOBrOHCHOHODryHCl+-t-BuOK+H/H2OCHOO试设计PhTM28的合成路线。合成CO2HTM29O试设计TM30的合成路线。TM309百度文库-让每个人平等地提升自我31、[合成]32、你如何制备CO2HTM32[合成]NaOEtCO2EtCO2EtCO2EtO试设计TM31的合成路线。+CO2EtCO2Et1.LiAlH42.PBr3Br_1.OH/H2OCO2Et2.HO+3TM323.heat10百度文库-让每个人平等地提升自我33、[合成]34、[合成]35、CHOOHH试设计TM33的合成路线。CO2HCO2Et2NaOEtCO2EtBrBr_CO2Et1.OH/H2OCO2Et+2.H3O3.heatTM33TM34O1.NaOEtCO2Et2.OCO2EtHOOHOOBrH+1.NaNH2O2.CH3IOHCl/H2OOH2/Pd/BaSO4TM34合成TM3511百度文库-让每个人平等地提升自我[分析]36、[合成]37、合成OTM37[合成]38、HTM38合成CO21.Br2/FeCl32.Mg/Et2O1.HCHOMgCl2.H3O+3.HClClMg/Et2OMgX1.CdCl2Cl2.aCHObCNCH2OHBrBrOHOBrH++HCHOOHOH...
