中国组织工程研究与临床康复第14卷第16期2010–04–16出版JournalofClinicalRehabilitativeTissueEngineeringResearchApril16,2010Vol.14,No.16ISSN1673-8225CN21-1539/RCODEN:ZLKHAH29111DepartmentofStomatology,theAffiliatedHospitalofMedicalCollege,QingdaoUniversity,Qingdao266000,ShandongProvince,China;2YantaiZhenghaiBio-TechnologyCo.,Ltd.,Yantai264000,ShandongProvince,ChinaXieMiao-miao★,Studyingformaster’sdegree,DepartmentofStomatology,theAffiliatedHospitalofMedicalCollege,QingdaoUniversity,Qingdao266000,ShandongProvince,Chinaanne00007@163.comCorrespondenceto:ZhaoBao-dong,Master,Professor,Master’ssupervisor,Chiefphysician,DepartmentofStomatology,theAffiliatedHospitalofMedicalCollege,QingdaoUniversity,Qingdao266000,ShandongProvince,ChinaReceived:2010-01-26Accepted:2010-03-061青岛大学医学院附属医院口腔科，山东省青岛市266000；2烟台正海生物技术有限公司，山东省烟台市264000谢苗苗★，女，1982年生，山东省青岛市人，汉族，青岛大学医学院在读硕士，主要从事口腔种植的研究。anne00007@163.com通讯作者：赵保东，硕士，教授，硕士生导师，主任医师，青岛大学医学院附属医院口腔科，山东省青岛市266000中图分类号:R318文献标识码:B文章编号:1673-8225(2010)16-02911-05收稿日期：2010-01-26修回日期：2010-03-06(20100126018/M·Z)口腔修复膜材料在牙种植中引导骨再生的效应★谢苗苗1，赵保东1，王维英1，于龙2，张晓奇2EffectsoforalbiofilmonguidedboneregenerationindentalimplantXieMiao-miao1,ZhaoBao-dong1,WangWei-ying1,YuLong2,ZhangXiao-qi2AbstractBACKGROUND:Heal-alloralbiofilmisamaterialutilizedinrepairingoralmucosaandsofttissuesdefectsandcharacterizedbydegradation,easilypreparation,longpreservedduration,convenienttransportationandgoodossification,whichhasbeenwidelyusedindentalimplantasguidedboneregenerationmaterials.OBJECTIVE:TochecktheclinicaleffectiveofHeal-alloralbiofilmonguidedboneregenerationindentalimplant.METHODS:Atotalof72patientswithbonedefectsintheimplantationareawereselectedassubjects,whoweredividedintocontrolgroupandexperimentalgroupatrandom.BonedefectsaroundimplantswererepairedbyguidedboneregenerationtechniquewithBME-10XmedicalcollagenmembraneandHeal-alloralbiofilmrespectively.X-rayandclinicalexaminationweretakenat1and3monthsafterimplantation.Theamountofnew-formedbonetissuewasevaluatedwhenstageIIoperationwasperformed.RESULTSANDCONCLUSION:InstageIIoperation,osseointegrationwasformedbetweenimplantsandbonetissueinall72patients.Theaveragerateofboneformationwas92%intheexperimentalgroupwhile91%inthecontrolgroup.Allimplantsweresuccessfullyrepairedwithimplantdenture.Occlusalfunctionwasrestoredsuccessfullywithall72implantsduringthefollow-upperiodof3-24monthsafterrestoration.AsanalternativeoptionofBME-10Xmedicalcollagenmembrane,Heal-alloralbiofilmcanbeusedinguidedboneformationclinically.XieMM,ZhaoBD,WangWY,YuL,ZhangXQ.Effectsoforalbiofilmonguidedboneregenerationindentalimplant.ZhongguoZuzhiGongchengYanjiuyuLinchuangKangfu.2010;14(16):2911-2915.[http://www.crter.cnhttp://en.zglckf.com]摘要背景：海奥口腔修复膜作为可降解的脱细胞真皮基质，是用于修复口腔黏膜及软组织缺损的材料，由于具有可降解、易于制备、保存时间长、运输和贮存方便、成骨效果好等优点，现在也已开始作为引导骨再生材料用于种植。目的：验证海奥口腔修复膜在种植中作为屏障膜引导骨再生的临床效果。方法：选择种植术区存在骨缺损的患者72例，均为单颗牙缺失，按随机原则分为对照组和试验组，分别采用博特医用胶原膜和海奥口腔修复膜行“引导性骨再生”技术修复骨缺损。骨移植物均为天博骨粉...
