论文题目：PharmacokineticandpharmacodynamicstudiesontheantiviruseffectsofA(一种中草药)againstvirusB（一种病毒）所投杂志：LifeSciences投稿结果：这次大修后又经过一次小修，被接受发表编辑信内容（注：有删节）：DearMr.XXX,Yourmanuscripthasbeenexaminedbytheeditorsandqualifiedreferee.WethinkthemanuscripthasmeritbutrequiresrevisionbeforewecanacceptitforpublicationintheJournal.Carefulconsiderationmustbegiventothepointsraisedinthereviewercomments,whichareenclosedbelow.Ifyouchoosetosubmitarevisionofyourmanuscript,pleaseincorporateresponsestothereviewercommentsintotherevisedpaper.Acompleterebuttalwithnomanuscriptalterationsisusuallyconsideredinadequateandmayresultinlengthyre-reviewprocedures.Aletterdetailingyourrevisionspoint-by-pointmustaccompanytheresubmission.YouwillberequestedtouploadthisResponsetoReviewersasaseparatefileintheAttachFilesarea.Weaskthatyouresubmityourmanuscriptwithin45days.Afterthistime,yourfilewillbeplacedoninactivestatusandafurthersubmissionwillbeconsideredanewmanuscript.Tosubmitarevision,gotohttp://ees.elsevier.com/lfs/andloginasanAuthor.YouwillseeamenuitemcalledSubmissionNeedingRevision.Youwillfindyoursubmissionrecordthere.Yourssincerely,JosephJ.Bahl,PhDEditorLifeSciencesFormatSuggestion:PleaseaccesstheGuidetoAuthorsatourwebsitetochecktheformatofyourarticle.PayparticularattentiontoourReferencesstyle.Reviewers'comments:Reviewer#1:XXXXX（略）Reviewer#2:XXXXX（略）Editorsnoteandsuggestions:（注：编辑的建议）Title:Re-writethetitletoreadmoresmoothlyincontemporaryEnglish>>>PharmacokineticandpharmacodynamicstudiesoftheantiviraleffectsofAagainstvirusB.Abstract:Re-writetheabstracttoreadmoresmoothly.A,analkaloidisolatedfromC(注：一种中草药),wastestedforantiviralactivityagainstvirusB.BothinvitroandinvivoassaysalongwithserumpharmacologicalexperimentsshowedAtohavepotentantiviralactivity.ThepharmacokineticprofileofAinSprague/DawleyratplasmaafteroraladministrationwasmeasuredbyHPLC.Bloodsamplestakenatselectedtimepointswereanalyzedtostudypotentialchangesinantiviralpharmacodynamicsasmeasuredbyinfectivityofviruses.FromthesimilarityoftheserumconcentrationprofilesandantiviralactivityprofilesitisconcludedthatAitself,ratherthanametabolite,exertedtheeffectagainsttheviruspriortobioinactivation.TheneedforeffectiveclinicalagentsagainstvirusBandtheseresultssuggestthepossibilityofbenefitfromfurtherexperimentswithA.Theauthorsshouldchecktobesurethatthetermsbloodsamples,plasmaandserumarealwaysusedappropriatelythroughouttheabstractandtext.Introduction:somesentencescanbemadelesspassive.example1stparagraph>>>>Aappearstobethemostimportantalkaloidisolatedfromtheplant,itsstructuralformulaisshowninFig1....Whileitproducedageneralinhibitionofantibodyproductionlymphocyteproliferationwasstimulated(XiaandWang,1997).ThesepharmacologicalpropertiessuggestapotentialuseinthetreatmentofviralmyocarditisagainstvirusBthatcouldbestudiedinexperimentsincellcultureandanimals.>>>Theauthorsshouldchecktheentiremanuscriptforspellingerrors(examplegiven:inyourtextalkaloidisincorrectlyspelledalkaloid)>>>Theauthorsshouldreadtheguidelinestotheauthorsandnotincludethefirstnameoftheauthorsbeingcitedinthetext.Inthereferencesectionthefirstnameshouldbeabbreviatedasshownintheguidelinetoauthors(thustheearliertextreferenceshouldbe(Liuetal.,2003)andtheremainingoneshouldbe(Chenetal.,2002)>>>>>Theauthorsinsteadofdirectlyansweringthefirs...
