2025年早期Vogt小柳原田病的眼底特征和治疗分析VIP专享VIP免费

早期 Vogt—小柳原田病的眼底特性和治疗分析 作者：邵玲杜敏闫淑来源：《中国医学创新》第 35 期 【摘要】 目的：分析早期 Vogt-小柳原田病（VKH）的临床特性和治疗预后。办法：回想性分析 7 月-4 月本院收治的 VKH 患者 27 例作为研究对象，共 54 眼，进行常规视力、裂隙灯检查、间接眼底镜、眼底彩色摄影、荧光素眼底血管造影（FFA）、光学相干断层扫描（OCT）等检查，并予以激素治疗，随访观察六个月，总结分析眼底病变特性及治疗效果。成果：眼底体现为视乳头水肿、视网膜水肿、浆液性视网膜脱离；FFA 体现为早期针尖样强荧光点，晚期视盘渗漏及视网膜多湖状荧光素积存。OCT 体现为神经上皮层多发性脱离。激素治疗后患者视力均明显提高。结论：眼底体现、FFA、OCT 等有助于早期 VKH 的诊疗，早期系统规范化的激素治疗，可有效控制炎症，改善视力。 【核心词】 Vogt- 小柳原田病； 眼底荧光血管造影； 光学相干断层扫描； 治疗 【Abstract 】 Objective：To investigate the clinical characteristics and therapeutic outcomes of early Vogt-Koyanagi-Harada（VKH ） disease.Method：27 patients（54 eyes ） with VKH in our hospital from June to April were selected as the research objects.The examinations of visual acuity，slit lamp，indirect ophthalmoscopy，fundus color photography，fundus fluorescence angiography（FFA ） and optical coherence tomography（OCT ） were given to the patients.All patients were treated with corticosteroid.They were given follow-up for 6 months.The characteristics of fundus lesions and treatment effect were summarized and analyzed.Result：The fundus was characterized by papilledema，edema of retina and serous retinal detachment.FFA showed tip sample strong fluorescence at the early stage and optic disc leakage and multiple hyper-fluorescent pool in retina at the late stage.OCT showed multiple detachment of nerve epithelium.The visions of all patients were improved after hormonotherapy.Conclusion：The appearance of fundus，FFA and OCT are useful for the di...