摘 要年产 2 亿片三拗片生产工艺设计摘 要实验以产品的不同点和 GMP 的相关要求，从实际情况出发，对产品生产工艺做出合理的分析和演示。生产设计的步骤主要是以下几点（1）生产设计。根据《中国药典》2012 年版三拗片的车间生产工艺和生产方法，计算并画出生产工艺流程图。（2）反应料计算。（2）根据生产任务及生产制度确定批量为 200 万片，在 200 万片批量的基础上完成各工序的物料衡算。（3）设备选型。利用各个生产步骤的物料投入含量和产率，根据各个基本操作各类型的生产范围，选出设备的最佳型号，合理的安排生产工作人员进行周期性工作。（4）车间设置。保证生产条件合理，生产安全以及环境保护良好的原则下，按照分类和就近原则，对车间的整体布局进行设计，达到车间设计的最佳效果。（5）非工艺设计。根据《建筑设计防火规范》等其他的规范和生活标准，从废物处理、安全防火以及劳动安全等多方面对非工艺进行处理。关键词：三拗片；车间设计；生产工艺设计 目 录AbstractBased on the differences of products and the requirements of GMP, this paper makes a reasonable analysis and demonstration of the production process from the actual situation. The steps of production design are mainly as follows (1) production design. According to the workshop production process and production method of the 2012 edition of Chinese pharmacopoeia, the flowchart of production process is calculated and drawn. (2) calculation of reaction material. (2) according to the production task and production system, the batch of 2 million pieces is determined, and the material balance of each process is completed on the basis of 2 million pieces of batch. (3) equipment selection. Using each step of production material input content and yield, according to the basic operation of various types of production range, choose the best type of the equipment, the arrangement of the reasonable production staff work periodically. (4) workshop setting. Ensure reasonable production conditions, production sa...
