探讨关腹前曲马多对上腹部术后患者早期恢复质量的影响 【关键词】 探讨 摘要:目的:探讨关腹前曲马多对上腹部术后患者早期恢复质量及并发症的影响。方法:42 例上腹部择期手术患者随机均分为两组:T 组和 C 组。T 组于关腹前静脉给予曲马多,C 组给等量生理盐水。手术结束后患者在恢复室滞留 90min,观察患者恢复质量及并发症。结果:两组患者术后呼名睁眼时间、拔管时间及定向力恢复时间差异无显着性;但 T 组的最大 VAS 评分远低于 C 组,观察期间需要追加阿片类镇痛药者例数也明显少于 C 组。两组患者术后恶心、呕吐、高血压、心动过速、呼吸抑制等并发症的发生率差异无显着性。结论:关腹前曲马多有助于提高患者术后早期恢复质量而不增加并发症。 关键词:曲马多;全身麻醉;恢复质量 Wound Closure Tramadol Administration Improves Quality of Recovery without Increasing side Effects in the early Stage after Upper Abdominal Operation QU LI-zhe,et al (Shanghai TCM Hospital, Shanghai 200071, China) Abstract:Objective: To evaluate the effects of tramadol administration at wound closure on recovery quality in patients undergoing upper abdominal surgery. Methods: 42 ASA I~II patients were allocated into two groups (n=20 in each) to receive either tramadol 2mg/kg (group T) or placebo saline (group C) iv at the time of wound closure. All patients stayed in recovery room for 90min before returning the ward , during this period, the times to eye opening, orientation, and tracheal extubation, as well as maximal pain score by VAS were observed; and the incidence of side effects including nausea/vomiting, tachycardia, hypertension, tachypnea, drowsiness and respiratory depression were also noted. Results: No statistically significant difference was found between the two groups in respect to the times to eye opening, orientation, and tracheal extubation (), but the maximal VAS score was markedly lower in group T than that in group C (),...