摘要神经系统疾病在世界范围内严重影响着人们的生活，帕金森病（Parkinson’sdisease，PD），也称作特发性或原发性帕金森病，就是一种最常见的神经系统疾病。但是由于帕金森病的确切病因目前仍不清楚，所以对于帕金森病的检测和诊断仍旧比较复杂近年来帕金森病与语音障碍之间联系的研究愈发受到重视，许多语音信号处理的算法被提出，用来对帕金森病的患病情况进行预测。目前的研究大多数是通过采集受试者的语音信号来进行帕金森病的诊断，其效果大多数比较好，成功的反映了语音障碍对帕金森病之间的联系。本研究构建了一个语音检测帕金森病的系统。该系统通过采集受试者的语音信号，利用语音信号处理的技术，从中提取多种语音障碍特征，接着通过使用多种人工智能的算法，对受试者进行帕金森病的诊断和其帕金森病患病严重程度的评估。同时将该系统放入手机应用的后端中，实现对帕金森病的远程诊断和病情监控。本研究为实现了帕金森病的诊断和疾病评估方便化、远程化提供了一定的贡献，同时可以作为决策支持工具，对医生的治疗和诊断提供相应的辅助。关键词：帕金森病；语音障碍；远程诊断；人工智能；手机应用ResearchonDetectionMethodofSpeechDisorderinParkinson’sDiseaseAbstractNeurologicaldiseasesseriouslyaffectpeople’slivesintheworldwide.Parkinson’sdisease(PD),alsoknownasidiopathicoridiopathicParkinson’sdisease,isoneofthemostcommonneurologicaldiseases.ThedetectionanddiagnosisofParkinson’sdiseasearecomplex,becausethespecificcausesofParkinson’sdiseaseremainelusive.ThefieldoftheconnectionbetweenParkinson’sdiseaseandspeechdisorderbecomesmoreandmoreattractiveinrecentyears,andthus,numerousspeechsignalprocessingalgorithmshavebeenproposed,aimingtopredicttheonsetofParkinson’sdiseases.MostofthestudiesaredesignedtodiagnoseParkinson’sdiseasesbycollectingspeechsignalsfromsubjects,andthemajorityofthealgorithmsareeffective,whichcansuccessfullyreflecttheconnectionbetweentheParkinson’sdiseasesandspeechdisorder.ThisstudyconstructedaspeechdetectionsystemforParkinson'sdisease.Thesystemcanextractvariousdysphoniafeaturesfromthespeechsignalcollectedfromsubjectsbythetechniquesofspeechsignalprocessing.Subsequently,thesystemcandiagnoseParkinson’sdiseasesandassesstheseverityofParkinson’sdiseasebyvariousartificialintelligencealgorithms.Moreover,thesystemshouldbeputintothebackgroundofmobilephoneapplicationstorealizetheremotediagnosisandconditionmonitoringofParkinson’sdisease.ThisstudycontributestotheconvenienceandremoteoftheParkinson’sdisease’sdiagnosisandevaluation.Itcanalsobeutilizedasadecision-supportmeansofprovidingtheassistanceforthedoctor'streatmentanddiagnosis.KeyWords：Parkinson’sDisease；SpeechDisorders；RemoteDiagnosis；ArtificialIntelligence；MobileApplication目录摘要.........................................................................................................................................IAbstract......................................................................................................................................II引言.........................................................................................................................................11帕金森病与语音障碍.............................................................................................................51.1目前帕金森病的诊断方法..........................................................................................51.2帕金森病人与语音障碍..............................................................................................51.3语音障碍检测帕...
