目录第一章绪论.............................................................31.1前言...........................................................31.2研究目标以及内容.................................................5第二章醋酸纤维素抗菌膜的构建及表征.....................................72.1实验部分.........................................................72.1.1实验原料与试剂.............................................72.1.2实验仪器...................................................72.1.3实验方法...................................................82.1.3.1二苯甲酮类离子液的合成................................82.1.3.2醋酸纤维素纤维膜的制备................................92.1.3.3离子液功能化纤维膜的制备..............................92.1.3.4离子液功能化纤维膜的抗菌性能测定.....................102.1.4表征方法..................................................102.2结果与讨论......................................................102.2.1二苯甲酮类离子液合成......................................102.2.2改性前醋酸纤维素膜的观测结果与分析........................112.2.3改性后醋酸纤维素膜的表征结果与分析........................122.2.4改性后醋酸纤维素膜的抗菌表征结果..........................142.3小结..........................................................15第三章结论............................................................17参考文献...............................................................18致谢...................................................................20紫外辐照一步法构建醋酸纤维素抗菌膜摘要静电纺丝是一种用于快速制备一维纳米材料的方法，具有快速、方便的特点，所制备的纤维直径可从几十个纳米到几微米，具有较高的孔隙率及比表面积，可携带大量的释放性药物。若在纳米纤维的表面接枝上抗菌剂进行修饰，便可制得具有抗菌功能的纤维膜，在生物医用材料领域有着广泛的应用。本文对抗菌的静电纺丝膜进行研究，以期获得高抗菌效率的静电纺丝膜。本课题首先通过控制静电纺丝过程中的纺丝液浓度、电压值、接收距离、进给速率、纺丝液用量和滚筒转速等参量制得表面平整、直径均一的醋酸纤维素（CA）纳米纤维膜，用扫描电子显微镜（SEM）对其形貌进行观察。再通过化学合成制得一种二苯甲酮类离子液体，运用核磁共振波谱表征其化学结构。随后通过紫外光照将二苯甲酮类离子液接枝到CA膜的表面获得改性CA膜，通过傅里叶红外光谱仪及X射线光电子能谱对其进行表征。最后再进行抗菌测试，表征改性CA膜的抗菌性能。关键词：静电纺丝醋酸纤维素纳米膜抗菌AbstractElectrostaticspinningisafastandconvenientmethodfortherapidpreparationofone-dimensionalnanomaterials.Thediameterofthefiberisfromnanometerstomicrometers.Thefiberhashighporosityandspecificsurfacearea,andcancarrydrugstorelease.Iftheantibacterialagentsaremodifiedonthenano-fibersurfaces,itcanbemadeoffibermembranewithantibacterialfunction,whichiswidelyusedinthefieldofbiomedicalmaterials.Inthispaper,antibacterialspinningfilmsarestudiedinordertoobtainthehighantibacterialefficiencyofelectrospinningfilm.Inthisstudy,firstly,smoothsurfaceanduniformdiameterofcelluloseacetate（CA）nanofibermembraneswereproducedbycontrollingelectrospinningsolutionconcentration,voltage,receivingdistance,feedrate,volumeofdopeandrollerspeed.Itsmorphologywasobservedbyscanningelectronmicroscopy（SEM）.Sceondly,adiphenylketoneionicliquidwassynthesizedandcharacterizedbynuclearmagneticresonancespectra（NMR）.ThenthemodifiedCAfilmswereobtainedbygraftingthediphenylketoneionicliquidontothesurfaceoftheCAmembrane.Theionicliquid-modifiedCAfilmswerech...
