精品文档---下载后可任意编辑乳腺癌耐药蛋白(ABCG2)在卵巢癌中的表达及意义的开题报告题目:乳腺癌耐药蛋白(ABCG2)在卵巢癌中的表达及意义摘要:卵巢癌是一种常见的妇科恶性肿瘤,在治疗中常常出现耐药现象。乳腺癌耐药蛋白(ABCG2)是一种 ATP 结合盒转运蛋白,在多种细胞类型中均有表达。近年来的讨论表明,ABCG2 在卵巢癌的化疗耐药中起着重要作用。本讨论将探讨 ABCG2 在卵巢癌组织中的表达情况及其与临床特征的关系,以期为卵巢癌的临床诊断与治疗提供新的思路和方法。关键词:乳腺癌耐药蛋白;ABCG2;卵巢癌;耐药性;治疗Abstract:Ovarian cancer is a common gynecological malignant tumor, and drug resistance often occurs during treatment. Breast cancer resistance protein (ABCG2) is an ATP-binding cassette transporter protein that is expressed in multiple cell types. Recent studies have shown that ABCG2 plays an important role in chemoresistance of ovarian cancer. This study aims to explore the expression of ABCG2 in ovarian cancer tissues and its relationship with clinical features, in order to provide new ideas and methods for the clinical diagnosis and treatment of ovarian cancer.Keywords: breast cancer resistance protein; ABCG2; ovarian cancer; drug resistance; treatment