II摘要口腔癌（oral cancer，OPC）是头颈部最常见的恶性肿瘤（非黑色素皮肤瘤除外），在不同的年龄、不同区域的人群中发病率均有一定的差别。随着人们生活水平的日益提高，越来越多的人们开始关注口腔疾病方面的问题，而口腔癌的发生、发展、侵袭及转移是一个多基因参与表达并且多步骤反应的复杂的生物学过程，其与吸烟、饮酒、病毒的感染及不良饮食习惯等危险因素有着密切的联系。因此本文将对近年来有关口腔癌发病的相关因素如年龄和性别、种族差异、不良饮食习惯、相关微生物以及分子生物学机制等方面的研究进行综述。关键词：口腔癌；危险因素；微生物；机制IAbstractOral cancer is the most common malignancy of the head and neck (excluding nonmelanoma skin cancer),and in different age,different areas of the crowd have certain difference. With the improvement of people’s living standard ,more and more people begin to pay attention to the problems of oral diseases. However ,the occurrence ,development,invasion and matastasis of oral cancer is a complex biological process in which multi-gene are involved in expression and multistep reactions ,it is closely related to dringking smoking,virus infection, and poor diet. So this paper will summarize the recent advances on the risk factors such as age and sex,racial difference ,poor dietary habit,related microbiology and molecular biological mechanism of oral cancer.Key words:Oral cancer;Risk factors;Microbiology;Mechanism1目录摘要..................................................................................................................IAbstract.........................................................................................................II1. 口腔癌.........................................................................................................11.1 概述........................................................................................................................11.2 口腔癌的病理分类及组织学特点........................
