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ICU系列幻灯安徽省立医院重症医学科周树生NEnglJMed2003;348:1546-1554NEnglJMed2003;348:1546-1554IntJAntimicrobAgents.2008;32:S87-91IntJAntimicrobAgents.2008;32:S87-91NosocomialBloodstreamInfectionsinUSHospitals:Analysisof24,179CasesfromaProspectiveNationwideSurveillanceStudy.NosocomialBloodstreamInfectionsinUSHospitals:Analysisof24,179CasesfromaProspectiveNationwideSurveillanceStudy.ClinInfectDis.2004Aug1;39(3):309-17.CNSStaphylococcusaureusEnterococcCandidaspecies(%)0153045ClinInfectDis.2003May1;36(9):1103-10Atotalof2340patientswithunderlyingmalignancywereidentifiedamong22,631episodesofnosocomialBSIsinaprospectivelycollecteddatabasefor49hospitalsintheUS.44.733.425.917.630.211.611.58.5107(39.5%)patientswithisolatedcandidemia,77(28.4%)withinvasivecandidiasis.In37%ofthecases,candidemiaoccurredwithinthefirst5daysafterICUadmission.CritCareMed.2009May;37(5):1612-8CritCareMed.2009May;37(5):1612-8OnehundredeightyICUsinFranceOnehundredeightyICUsinFranceAnnSurg.2001Apr;233(4):542-8.PelzRK,HendrixCW,SwobodaSM,IntJAntimicrobAgents.2009Sep;34(3):205-9IntJAntimicrobAgents.2009Sep;34(3):205-9ConsensusstatementonthemanagementofinvasivecandidiasisinICUintheAsia-PacificRegionConsensusstatementonthemanagementofinvasivecandidiasisinICUintheAsia-PacificRegionCHINASCANteamNonalbicans>54.7%C.albicans41.8%mixedinfectionotherCandidaspeciesDiagnosticconfirmationwasbasedsolelyonatleastonepositivebloodculturein290(94.8%)casesDiagnosiswasconfirmedbyhistopathologyinonepatient(0.3%)InvasivecandidiasisinICUinChina:amulticentreprospectiveobservationalstudyInvasivecandidiasisinICUinChina:amulticentreprospectiveobservationalstudyJAntimicrobChemother.2013Mar29.1-9FengmeiGuo1,YiYang1,YanKang,etal.JAntimicrobChemother.2013Mar29.1-9FengmeiGuo1,YiYang1,YanKang,etal.Anidulafunginforthetreatmentofcandidaemia/invasivecandidiasisinselectedcriticallyillpatientsClinMicrobiolInfect.2012July;18(7):680–687.C.kefyr=乳酒念珠菌;C.dubliniensis=都伯林念珠菌;C.pelliculosa=菌膜念珠菌JClinMicrobiol.2012;50(6):2156–2158.FirstCaseReportofBloodstreamInfectionDuetoaCandidaSpeciesCloselyRelatedtotheNovelSpeciesCandidapseudorugosaThepatientwasa49-year-oldwomanfromBuenosAires;Onelimitationwasthatmostlaboratoriesemployedcommercialidentificationmethodstoidentifytheisolates,andthesemethodsmaymisidentifysomespeciesTheC.pseudorugosaisolatesdescribedseemstoberesistanttoamphotericinBcaspofungin,itraconazole,andnystatinInvasiveScedosporiumapiospermuminfection：onecasereport刘宝,周树生等,中国感染与化疗杂志.2009;9(6);466-469尖端赛多孢子菌InvasiveScedosporiumapiospermuminfection：onecasereport刘宝,周树生等,中国感染与化疗杂志.2009;9(6);466-469InvasiveScedosporiumapiospermuminfection：onecasereport刘宝,周树生等,中国感染与化疗杂志.2009;9(6);466-469CritCare.2008;12(1):R5CritCare.2008;12(1):R5Impactofinvasivefungalinfectiononoutcomesofseveresepsis:amul-ticentermatchedcohortstudyincriticallyillsurgicalpatientsOutcomesofcandidemicsepticshockpatientscomparedwithbacteremicsepticshockpatientsOutcomesofcandidemicsepticshockpatientscomparedwithbacteremicsepticshockpatientsCritCareMed.2002Aug;30(8):1808-14.CritCareMed.2002Aug;30(8):1808-14.InpatientswithsuspectedVAP,Candidaspp.airwaycolonizationisfrequentandassociatedwithincreasedriskforMDR(P.aeruginosa)bacteriaisolation.Similarly,acase–controlstudyshownthatantifungaltherapywaslikelytoprevents...