光生物调节作用(photobiomodulation, PBM)是一个正在发展的生物医学VIP免费

国际光能杂志（InternationalJournalofPhotoenergy,2009~2010年SCI影响因子1.494）光生物调节作用专刊征文（http://www.hindawi.com/journals/ijp/si/pbm/）光生物调节作用（photobiomodulation,PBM）是一个正在发展的生物医学研究领域。PBM利用低水平/强度/功率的激光或单色光调节生物功能，但没有不可逆的损伤。1960年激光发明以来，PBM广泛用于镇痛、消除炎症、加快伤口愈合和毛发生长、预防细胞死亡和组织损伤、改善血液循环然而，PBM在主流医学领域还颇有争议。尽管有大量的实验室和临床研究，PBM的机理依然不是十分清楚。其中的关键是PBM依赖于实验对象的初始状态。Karu(1998)年指出，低功率激光对功能正常的细胞没有PBM，只有功能失调的细胞可以产生PBM。另外，照射强度和照射时间等照射参数的选择也十分复杂。因为对实验对象的初始状态和光照剂量没有予以足够的重视，很多作者报道了PBM的负面结果，即使是正面结果也包含相互矛盾的数据。因此，PBM还需要深入的研究。尽管现状不容乐观，新的令人兴奋的发现正在不断出现。本专刊邀请作者将原创性实验或机理研究及其应用的综述投稿。专刊包括以下内容，但不限于以下内容：*内稳态与光生物调节作用*线粒体与与光生物调节作用*信号转导与光生物调节作用*低强度激光或单色光*中等强度激光或单色光*光生物调节作用治疗*伤口愈合*激光针灸投稿前请仔细阅读杂志的作者须知（http://www.hindawi.com/journals/ijp/guidelines.html），并采用在线投稿（http://mts.hindawi.com/）：投稿截止日期：2011年10月15日第一轮审稿日期：2012年1月15日发表日期：2012年4月15日客座主编*刘承宜广州华南师范大学激光运动医学实验室（liutcy@scnu.edu.cn）客座编辑*TiinaI.KaruInstituteofLaserandInformationTechnologieofRussianAcademyofSciences,Troitsk,MoscowRegion,Russia*RuiDuan,DepartmentofMolecularBiologyandGenetics,JohnsHopkinsUniversitySchoolofMedicine,Baltimore,USA*LutzWilden,PrivatpraxisfürhochdosierteLow-Level-Lasertherapie,BadFüssing,GermanyPhotobiomodulationSpecialIssueofInternationalJournalofPhotoenergy(2009~2010SCIIF1.494)(http://www.hindawi.com/journals/ijp/si/pbm/)CallforPapersPhotobiomodulationisadevelopingbiomedicalpracticeinwhichalow-level/intensity/powerlaserormonochromaticlightisutilizedtomodulatebiologicalfunctionswithoutirreversibledamage.Ithasbeenwidelyusedtoreducepainandinflammation,acceleratewoundhealingandhairgrowth,preventcelldeathandtissuedamage,andimprovebloodcirculationsincetheinventionoflasersinthe1960s.Photobiomodulationremainscontroversialinmainstreammedicine.Despitemanylaboratoryexperimentsandclinicaltrials,thecellularandmolecularmechanismsofphotobiomodulationcontinuetobeelusive.Amainreasonisthattheinitialphysiologicalstateofthetreatmentobjectiscriticalforthetreatmentresponse.Forexample,asKaru(1998)haspointedout,therearenoeffectsoflow-powerlaserirradiationonthecellwhoseredoxpotentialissothatthecellnormallyfunctions.Inaddition,recentstudieshaveshowntherehasbeenthecomplexityofchoosingfromalargenumberofilluminationparameters,suchaswavelengthandtreatmentdosage(powerdensityandirradiationtime).Manynegativereportsareconfusingbecausetheydonotincludethedoseresponseorpayattentiontotheinitialstate.Evenpositiveresultscontainconflictingdata.Thus,futurestudiesneedtobecarriedoutcarefullyregardingthesefactors.Inspiteofthesemisleadingandconfusingpublications,newandexcitingfindingsarejustbeginning.Inthisspecialissue,weinviteauthorstopresentoriginalresearcharticles,aswellasreviewarticles,thatstudythemechanismsofphotobiomodulationanditsapplications.Potentialtopicsinclude,butarenotlimitedto:*Homeostasisandphotobiomodulation*Mitochondriaandphotobiomodulation*Signaltransductionandphotobiomodulation*Low-intensitylaserirradiationormonochromaticlight*Moderateintensitylaserirradiationormonochromaticlight*Therapeuticphotobiomodulation*Woundhealing*LaseracupunctureBeforesubmissionauthorsshouldcarefullyreadoverthejournal'sAuthorGuidelines,whicharelocatedathttp://www.hindawi.com/journals/ijp/guidelines/.ProspectiveauthorsshouldsubmitanelectroniccopyoftheircompletemanuscriptthroughthejournalManuscriptTrackingSystemathttp://mts.hindawi.com/accordingtothefollowingtimetable:ManuscriptDueOctober15,2011FirstRoundofReviewsJanuary15,2012PublicationDateApril15,2012LeadGuestEditor*TimonCheng-YiLiu,LaboratoryofLaserSportsMedicine,SouthChinaNormalUniversity,Guangzhou510631,China(liutcy@scnu.edu.cn)GuestEditors*TiinaI.Karu,InstituteonLaserandInformationTechnologiesofRussianAcademyofSciences,Troitsk142190,Russia*RuiDuan,DepartmentofMolecularBiologyandGenetics,JohnsHopkinsUniversitySchoolofMedicine,Baltimore,MD21205,USA*LutzWilden,PrivatpraxisfürHochdosierteLowLevelLasertherapie,Wilden,L.Kuralle16,94072BadFüssing,Germany