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CaseHistoryReportGeneralinformationName:TanGender:maleAge:37MaritalStatus:marriedOccupation:farmerBirthPlace:GaoyouCityJiangsuProvinceRace:HanSourceofHistory:himselfDateofAdmission:2015-11-21ChiefComplaintEdemaofbothlowerlimbsfor10days.PresentillnessTendaysago,thepatientdevelopedsymmetricconcaveedemaofbothlowerlimbswithnocause,andedemaofbotheyelidsarenotobvious,andleftituntreated.Aweeklater,hecametoourhospitalfordiagnosisandtreatment.PresentillnessLabsshowed:Blood-RTWBC11.37*109/L,HGB120g/L,PLT280*109/L;Urine-RT:BLD++,RBC27cells/ul;UrinePRO17.35g/L;Alb24.1g/L;TG2.12mmol/L,CHO9.78mmol/L.“NephroticSyndrome”wasdiagnosedandadmittedforfurtherdiagnosisandtreatment.PresentillnessSincetheonsetofsymptoms,hisspirit,sleep,appetiteandweighthavenotbeencompromised.Hisstoolandurinevolumearenormalwithfoams.Hedenieslumbodynia,hematuria,nocturia,thamuria,urgency,odynuria.PresentillnessHealsodeniesrashes,photosensitivity,alopecia,eyeormouthdryness,oralulcers,jointswelling,cough,chesttightness,andshortnessofbreath,abdominalpainetc.;Andhedeniestakingdrugsbeforetheonsetofsymptoms.PasthistoryDeniedhistoryoftuberculosisorviralhepatitis,diabetesmellitus,hypertension,coronaryheartdisease,etc.Deniedhistoryoftrauma,surgery,bloodtransfusion,etc.Deniedfoodordrugallergy.SystemreviewWehavenotfoundothersymptomsexceptedemaandfoamedurineinreviewofsystems.PersonalHistoryHispersonalhistoryandfamilyhistoryareallnotspecial.PhysicalexaminationT36.5℃HR78bpmRR18/minBP136/92mmHgGoodgeneralstateofhealth,skincolorisnormal,nocyanosis,nofaceedema,notonsillarenlargement.Noabnormalbreathsoundwasheard.Norales.Cardiacrhythmwasregular,nopathologicalmurmurs.Theabdomenisflatandsoft.Therewasnottenderness,reboundtendernessandpercussionpainonabdomenorrenalregion.Symmetricconcaveedemaofbothlowerlimbs.LaboratoriesNormalBlood-RT,Stool-RTC3,C4,Alt,TBil,DBil,Glu,BUN,PT,INR,UBJP,AFP,CEAHBsAg,HCV,HIVTSH,FT3,FT4RF,ASOβ2-MGANCA,ANA,dsDNA,Sm,SSA,SSBNormalB-USofkidneysandheartwerenormal.AbnormalAlb21.0g/L↓,Cre45.0umol/L,TG1.84mmol/L↑,CHO8.07mmol/L↑,HDL-C1.62mmol/L↑,LDL-C5.59mmol/L↑,ESR25mm/h↑,D-D1.12ug/ml↑IgG3.43↓,IgM0.33↓,IgA(normal)U-pro(24h):3.01g/24h↑,Ccr162ml/min↑Urine:PRO++,RBC33/uL↑,WBC27.2/uL,NAG46.4U/L↑DiagnosisandTreatmentDiagnosis:NephroticSyndromePresenttreatments:Furosemide20mgBIDValsartan80mgQDMetoprolol12.5mgBIDRosuvastatin10mgQDCalciumCarbonateandVitaminD3600mgQDPrednisone60mgQDRabeprazole20mgQDThankYou!