中国组织工程研究第16卷第11期2012–03–11出版ChineseJournalofTissueEngineeringResearchMarch11,2012Vol.16,No.11ISSN1673-8225CN21-1581/RCODEN:ZLKHAH2011DepartmentofPreventiveMedicine,SchoolofPublicHealth,GuangzhouMedicalCollege,Guangzhou510182,GuangdongProvince,ChinaWangJing★,Studyingformaster’sdegree,DepartmentofPreventiveMedicine,SchoolofPublicHealth,GuangzhouMedicalCollege,Guangzhou510182,GuangdongProvince,Chinawj31803@sina.comCorrespondingauthor:XiaoDe-sheng,Professor,Doctoralsupervisor,DepartmentofPreventiveMedicine,SchoolofPublicHealth,GuangzhouMedicalCollege,Guangzhou510182,GuangdongProvince,Chinaxiaodesheng@hotmail.comSupportedby:theNationalNaturalScienceFoundationofChina,No.31071038*Received:2011-11-25Accepted:2011-12-20雄性大鼠长期有氧运动期间血液铁状态与饮食铁含量的关系*★王婧，邝桂然，黄海鹏，王晓燕，袁利，肖德生Effectofdietaryironcontentsonhematologicalironstatusinmaleratswithlong-termaerobicexerciseWangJing,KuangGui-ran,HuangHai-peng,WangXiao-yan,YuanLi,XiaoDe-shengAbstractBACKGROUND:Effectsofexerciseonhematologicalironstatushavebeenextensivelystudiedinfemalerats,butthoseeffectshavenotbeenobservedinmalerats.OBJECTIVE:Toinvestigatetheeffectsofdietaryironcontentsandswimmingexerciseonhematologicalironstatusofmalerats.METHODS:Ninetyweaningmaleratswereassignedintothreegroups:dietaryirondeficiencygroup,dietaryironsufficiencygroupanddietaryhighironcontentgroup,andtheneachgroupwasfurtherdividedintoexercisegroupandsedentarygroup.Afteronemonthoffeedingwithdifferentironcontentsdiet,theratsineachexercisegroupenteredaswimmingprogramonceaday,lastingfor3months,andtheratsinthecorrespondingsedentarygroupsreceivedapproximatelythesameamountofhandlingastheexercisedrats,exceptforswimming.Animalswerefastedfor24hoursafterthelastexerciseregimenandthenbloodcollectionwastakenfromtheirheartsunderpentobarbitalanesthesiaforanalyzingrelatedindexofredbloodcellsandtotalironbindingcapacity(TIBC).RESULTSANDCONCLUSION:DietaryironcontentscouldsignificantlyaffectthemaineffectsofindexofredbloodandTIBC,andexercisecouldsignificantlyaffectthemaineffectoftheredcelldistributionandTIBC.Inthedietarylowironcontentgroups,thesedentaryratshadthechangesofirondeficiencywithanemia,buttheexercisedratshadthesignificantlylowerserumironandtransferrinsaturationandthesignificantlyhigherTIBC.Itshowedthatexerciseundertheconditionofdietaryirondeficiencycoulddeteriorateserumironstatus.Bothinthedietarysufficientirongroupandthedietaryhighironcontentgroup,exercisecouldsignificantlyincreaseredcelldistributionandTIBCwithnosignificantchangesofotherredbloodcellindexesandserumiron,itsuggestedthatexerciseundertheconditionofdietarysufficientironcontentmaynotinducethehematologicallowironstatus.WangJ,KuangGR,HuangHP,WangXY,YuanL,XiaoDS.Effectofdietaryironcontentsonhematologicalironstatusinmaleratswithlong-termaerobicexercise.ZhongguoZuzhiGongchengYanjiu.2012;16(11):2011-2014.http://www.crter.cnhttp://en.zglckf.com]摘要背景：运动对雌性大鼠血液铁状态的影响也已经得到广泛研究，但运动对雄性大鼠血液铁状态的影响仍不明确。目的：观察不同铁含量饮食以及游泳运动对雄性大鼠血液铁状态的影响。方法：断乳雄性SD大鼠90只，分为饮食低铁含量组、标准铁含量组、高铁含量组。每组再分为运动组和静息组。用不同的铁含量饲料喂养1个月后，运动组开始游泳，每天1次，持续3个月，静息组除不做运动外，其余处理同对应运动组。最后1次运动后，大鼠空腹24h，戊巴比妥钠麻醉下取静脉...
