下载后可任意编辑深部热疗联合同步放化疗对中晚期宫颈癌的近期疗效观察|化疗和热疗深部热疗联合同步放化疗对中晚期宫颈癌的近期疗效观察|化疗和热疗 [摘要] 目的：观察深部热疗加同步放化疗治疗晚期宫颈癌的临床疗效及不良反应。方法：80 例Ⅱ b~Ⅳa 期宫颈癌患者，随机均分为深部热疗加同步放化疗组（综合组）和同步放化疗组（对比组)，对比组行适形放疗配合同期化疗，顺铂 40 mg/m2 单药每周化疗，共 6 次；综合组放化疗方法同对比组，深部热疗每次治疗 60 min，每周 1~2 次，共 8~12 次。结果：综合组和对比组治疗结束后肿瘤完全缓解率、1 年期无瘤生存率比较，差异有统计学意义（P0.05）。结论热放化综合治疗可以提高患者近期疗效，且无严重的并发症，是中晚期宫颈癌治疗中的一种安全有效的模式。 [关键词] 宫颈癌；深部热疗；放疗；化疗 [ 中 图 分 类 号 ] R737.33 [ 文 献 标 识 码 ] A [ 文 章 编 号 ] 1674-4721（20XX）12（b）-０ 07－０ 3 Evaluate of short-term effect of hyperthermia combined with chemoradiation therapy in advanced cervical cancer SHI Xingyuan, ZHOU Tongchong, LIN Xiaodan, ZHANG Weijun Cancer Hospital of Guangzhou Medical College, Guangdong Province, Guangzhou xxxx, China [Abstract] Objective: To evaluate the short-term effect and acute toxicity of SR-1000 raidofrequency combined with chemoradiation therapy in advanced cervical cancer. Methods: Eighty women with invasive squamous cell carcinoma or adenocarcinoma of the cervix of stageⅡb-Ⅳa were enrolled. Patients were randomly divided into two groups who received one of two regimens: hyperthermic chemoradiotherapy (HCR) and chemoradiotherapy(CR). Full-dose 1下载后可任意编辑radiotherapy and 6 courses of chemotherapy was delivered to all patients according to plan. 8-12 courses of hyperthermia treatment were received by group HCR. Results: The complete remission and 1 year survival rate without cancer was significantly higher in groups HCR than in group CR. Toxicity was fully...
