精品文档。1欢迎下载名词解释Glossary第一章蛋白质的结构与功能Chapter 1 Structure and Function of Proteinpeptide bond(肽键):a covalent bond linking the α - amino group of one amino acid and the α -carboxyl group of another in a protein molecule.peptide (肽):a molecule containing two or more amino acids linked by peptide bond.primary structure of protein( 蛋 白 质 的 一 级 结 构 ): the amino acid sequence of a polypeptide.secondary structure of protein(蛋白质的二级结构): the spatial arrangement of local portions of a polypeptide chain.tertiary structure of protein(蛋白质的三级结构):the spatial arrangement of all the atoms of a protein or a subunit.quaternary structure of protein (蛋白质的四级结构):the spatial arrangement of a protein that consists of more than one folded polypeptide chain or subunit.subunit (亚基):an individual polypeptide chain that associates with one or more separate chains to form a complete protein.motif (模序):a substructure formed with two or more secondary-structure peptide segments that are drawn close to each other.domain (结构域) :a region within a protein, particularly within a large polypeptide, that functions in a semi-independent manner.positive cooperativity(正协同效应) :an effect that the binding of one ligand to a protein facilitates the subsequent ligand binding.allosteric effect(变构效应) : an effect that a small molecule, called an effector, noncovalently binds to a protein and alters its activity.isoelectric point (pI )of protein (蛋白质的等电点) :the pH at which a protein has an equal number of positive and negative charges and hence bears no net charge.denaturation of protein(蛋白质变性) : the disruption of the natively folded structure of a protein ca...