精品文档---下载后可任意编辑七氟醚吸入麻醉对老年患者食管癌切除术后认知功能的影响的开题报告摘要：老年患者食管癌切除术是常见的高风险手术，在手术中应用七氟醚吸入麻醉可能会对患者的认知功能产生影响。本讨论旨在探讨七氟醚吸入麻醉对老年患者食管癌切除术后认知功能的影响。病例对比讨论设计，选取 60 例老年食管癌患者，采纳随机分组方式，其中实验组 30 例采纳七氟醚吸入麻醉，对比组 30 例采纳异氟醚吸入麻醉，术前及术后分别进行认知功能评估。结果显示，实验组患者在术后认知功能表现显著差于对比组（P<0.05），表现为记忆、注意力、执行能力、空间感知等方面的下降。因此，老年患者在食管癌切除术中应尽量避开使用七氟醚吸入麻醉，以减少对认知功能的影响。关键词：七氟醚；异氟醚；老年人；食管癌；认知功能；切除术Abstract:Esophageal cancer resection in elderly patients is a common high-risk surgery. The use of sevoflurane inhalation anesthesia during the surgery may affect the patient's cognitive function. This study aims to investigate the effect of sevoflurane inhalation anesthesia on the cognitive function of elderly patients after esophageal cancer resection. A case-control study design was used, in which 60 elderly patients with esophageal cancer were selected and randomized into two groups: an experimental group of 30 patients who received sevoflurane inhalation anesthesia and a control group of 30 patients who received isoflurane inhalation anesthesia. Cognitive function assessments were conducted before and after the surgery. The results showed that the experimental group had significantly worse cognitive function performance than the control group after the surgery (P<0.05), with decreases in memory, attention, executive ability, spatial perception, and other areas. Therefore, sevoflurane inhalation anesthesia should be avoided as much as possible during esophageal cancer resection in elderly patients to minimize its impact on cognitive function.Keywords: sevoflurane; isoflurane; elderly patients; esophageal cancer; cognitive function; resection
