精品文档---下载后可任意编辑乙肝肝硬化患者皮质醇水平测定及并发感染前后皮质醇水平的动态变化的开题报告摘要：乙型肝炎（HBV）是世界上最常见的病毒性肝炎之一，患者常会进展为肝硬化，严重影响患者的生活质量和健康。皮质醇是一种主要由肾上腺皮质分泌的激素，在人体中具有重要的调节作用。有报道指出，肝硬化患者的皮质醇水平可能受到影响，但目前与 HBV 相关的皮质醇水平变化仍未得到充分的讨论。本讨论旨在确定 HBV 引起的肝硬化患者的皮质醇水平，并探究并发感染前后皮质醇水平的动态变化。讨论对象为 50 名 HBV 引起的肝硬化患者，他们将接受皮质醇水平检测和临床症状、医学记录的收集。此后，患者将接受 2 个月的康复治疗。治疗前后，将再次测定皮质醇水平，并收集相关的医学数据，以确定并发感染治疗对皮质醇水平的影响。本讨论的预期结果是，HBV 引起的肝硬化患者的皮质醇水平可能低于正常人的水平。经过 2 个月的治疗，患者的皮质醇水平可能会得到改善，但确切的预见还待进一步讨论。关键词：乙型肝炎；肝硬化；皮质醇；感染；康复治疗Abstract:Hepatitis B virus (HBV) is one of the most common viral hepatitis worldwide which can lead to liver cirrhosis, severely affecting patients’ quality of life and health. Cortisol is a hormone mainly secreted by the adrenal cortex in the human body, playing an important regulatory role. Some studies have suggested that cortisol levels may be affected in patients with liver cirrhosis, but the cortisol level changes related to HBV have not been fully investigated yet.This study aims to determine cortisol levels in HBV-induced liver cirrhosis patients and investigate the dynamic changes in cortisol levels before and after co-infection. The study will recruit 50 HBV-induced liver cirrhosis patients, who will undergo cortisol level testing and collection of clinical symptoms and medical records. After that, patients will receive 2 months of rehabilitation treatment. Before and after treatment, cortisol levels will be measured again, and relevant 精品文档---下载后可任意编辑medical data will be collected to determine the effect of co-infection treatment on cortisol levels.The expected outcome of this study is that cortisol levels in HBV-induced liver cirrhosis patients may be lower than those of normal individuals. After 2 months of treatment, patients’ cortisol levels may be improved, but the precise prediction awaits further research.Keywords: Hepatitis B; Liver cirrhosis; Cortisol; Infection; Rehabilitation treatment
