活血化瘀药佐治儿童痰热闭肺型支原体肺炎的疗效观察_朱永琴VIP专享VIP免费

第31卷第5期2013年5月中华中医药学刊CHINESEARCHIVESOFTRADITIONALCHINESEMEDICINEVol．31No．5May2013中华中医药1200学刊活血化瘀药佐治儿童痰热闭肺型支原体肺炎的疗效观察朱永琴，王艳，邬思远，徐巧，董勤(浙江中医药大学附属第一医院，浙江杭州310006)摘要:目的:探讨活血化瘀药治疗儿童痰热闭肺型支原体肺炎的临床疗效。方法:选取60例符合痰热闭肺型支原体肺炎诊断标准患儿，随机分成两组，治疗组、对照组各30例。所有患儿均使用阿奇霉素针10mg/(kg·d)静滴治疗5天，同时服用中药1周。治疗组在使用对照组的中药前提下加用活血化瘀药物，如丹参、桃仁、川芎、赤芍。观察患儿临床症状体征改善时间、病程、肺部炎症吸收时间等各项指标。结果:两组患儿热退时间、肺部罗音消失时间、住院时间，治疗组均优于对照组，经统计学分析，差异具有统计学意义(P＜0．05);咳嗽明显缓解时间治疗组较对照组有所缩短，但差异无统计学意义(P＞0．05);临床总体疗效治疗组显效率为93．3%，对照组为83．3%，经统计学分析差异具有统计学意义(P＜0．05)。结论:加用活血化瘀药对改善儿童痰热闭肺型支原体肺炎的临床症状、体征、病程等方面具有一定的优势，临床疗效显著。关键词:儿童;支原体肺炎;痰热闭肺型;活血化瘀药;临床疗效中图分类号:R563．12文献标志码:B文章编号:1673－7717(2013)05－1200－04ClinicalStudyonTreatingChildren＇sMycoplasmaPneumoniaeofthePatternofPhlegmandHeatObstructingLungwithHerbsforActivatingBloodCirculationandEliminatingStasisZHUYongqin，WANGYan，WUSiyuan，XUQiao，DONGQin(ZhejiangProvincialHospitalofTraditionalChineseMedicine，Hangzhou310006，Zhejiang，China)Abstract:Objective:Toinvestigatetheclinicalcurativeeffectofherbsforactivatingbloodcirculationandeliminatingstasisontreatingchildren＇smycoplasmapneumoniaewiththepatternofphlegmandheatobstructinglung．Methods:Atotalof60patientswithmycoplasmapneumoniae(thepatternofphlegmandheatobstructinglung)weredividedintotreatmentgroup(30cases)andcontrolgroup(30cases)atrandom．Thechildrenintwogroupsbothusedazithromycinbythedoseof10mg/(kg·d)forfivedays，andtookChineseherbforoneweek．Thetreatmentgroupaddedherbsforactivatingbloodcirculationandeliminatingstasis，likeDanshen，Taoren，Chuanxiong，Chishao．Someindexessuchasthethermalfadetime，thetimeofralesdisappearedandthelengthofstaywasobserved．Results:Thestatisticalanalysisofthetwogroupsinthethermalfadetimeandthedayofralesdisappeared，thelengthofstayprovedthatthetreatmentgroupwasbetterthanthecontrolgroup(P＜0．05);coughrelievingtimeinthetreatmentgroupwasshorterthanthatincontrolgroup，withoutstatisticantdifference(P＞0．05);ontheoverallclinicalefficacyevaluation，theexcellencerateoftreatmentgroupwas93．3%，thecontrolgroupwas83．3%，thetreatmentgroupwasbetterthanthecontrolgroupinclinicalcurativeeffect(P＜0．05)．Conclusion:Addingherbsforactivatingbloodcirculationandeliminatingstasishascertainadvantagesonimpro-vingclinicalsymptomsandsigns，shorteningcourseandsoon．Keywords:children;mucoplasmapneumoniae;patternofphlegmandheatobstructinglung;Chineseherbforactiva-tingbloodcirculationandeliminatingstasis;clinicalcurativeeffect收稿日期:2012－12－08作者简介:朱永琴(1966－)，女，浙江人，副主任医师，硕士研究生导师，硕士，研究方向:中西医结合治疗儿童呼吸系统、血液系统等疾病。支原体肺炎(MycoplasmalPneumonia)是由肺炎支原体引起的呼吸道感染性疾病。其在儿童呼吸道疾病中的发病率呈逐年上升趋势，有研究发现在小儿急性呼吸道感染中，肺炎支原体感染占了住院儿童的10%［1］。由于肺炎支原体对β－内酰胺类抗生素不敏感，目前西医治疗首选大环内酯类抗生素。考虑肺炎支原体的特点，并结合药物的稳定性、对胃肠刺激、肝肾功能...