中国普外基础与临床杂志2013年8月第20卷第8期ChinJBasesClinGeneralSurg,Vo1.20,No.8,Aug.2013·915·过伸体位对甲状腺手术患者椎动脉供血的影响及其与术后患者恶心呕吐的相关性分析孙少华,胡洪生,周文波,沈丰,吴红伟,房淑彬论著【摘要】目的探讨过伸体位对甲状腺手术患者术后椎动脉血流动力学的影响,并分析其变化与患者术后发生恶心呕吐的相关性。方法选取158例拟行甲状腺手术患者,分别测定术前6h及术后6h平卧位双侧椎动脉血流动力学指标(平均血流速度和平均血流量),并观察患者术后发生恶心呕吐的差异;同时选取同期89例行腹腔镜胆囊切除术(Lc)患者并观察其术后恶心呕吐情况,并与甲状腺手术患者进行对比。2组手术的麻醉方式和用药相同。结果甲状腺手术患者术后双侧椎动脉平均血流速度较术前明显降低<0.05),平均血流量较术前明显减少(P<0.05);发生0次、2次、3次、4次恶心呕吐患者甲状腺手术组明显多于LC组(P<0.05,P<0.01),发生恶心呕吐的持续时间(1次、2次、3次、4次)甲状腺手术组亦明显长于LC组(尸<0.01)。恶心呕吐的发生与甲状腺患者双侧椎动脉血流量的变化量及双侧血流速度变化量呈正相关(血流量变化量:=O.697,P=0.03;血流速度变化量:rs=0.897,P=0.01)。结论甲状腺手术过程中患者过伸体位对椎动脉血流动力学有一定的影响,同时对甲状腺手术患者术后发生恶心呕吐会有影响。【关键词】甲状腺;椎动脉;血流动力学;颈过伸体位【中图分类号】R653【文献标志码】AEffectsofNeckHyperextensiOnPositiononHemodynamicsofVertebralArteryFollowingThyroidectomyandCorrelationBetweenChangeofHemodynamicsandPostoperativeNauseaandVomitingSUNShao—hua,HUHong-sheng,ZHOUWen—bo,SHENFeng,WUHong-wei,FANGShu—bin..DepartmentofGeneralSurgery,DongfengGeneralHospitalAffiliatedofHubeiUniversityofMedicine,Shiyan442008,HubeiProvince,China;2.DepartmentofGeneralSurgery,HjishanHospitalAffiliatedofWannanMedicalCollege,Wuhu241002,AnhuiProvince,ChinaCorrespondingAuthor:FANGShu-bin,E—mail:husstome2OOO@yahoo.com.cn[Abstract]ObjectiveToapproachtheefectofneckhyperextensionpositiononhemodynamicsofvertebralarteryfollowingthyroidectomy,andanalyzethecorrelationbetweenthechangeofhemodynamicsandnauseaandvomiting.MethodsOnehundredandfifty—eightpatientswithpreparingforthyroidectomy(thyroidectomygroup)and89patientswithlaparoscopiccholecystectomy(LC,LCgroup)wereselected.Theanesthesiamethodandtheanesthesiadrugswerethesameintwogroups.Theindexesofhemodynamicsofthebilateralvertebralarteryat6hbeforeandafterthyroidectomyweremeasured.Thediferenceofnauseaandvomitingwasobservedandcomparedintwogroups.ResultsTheaveragebloodflowvelocityofthebilateralvertebralarteryreducedandthebloodflowdecreasedat6hafterthyroidectomyascomparedwithat6hbeforethyroidectomy(P<0.05).Theratesofnauseaandvomitingof0.2,3,4timesinthethyroidectomygroupweresignificantlyhigherthanthoseintheLCgroup(尸<0.05,P<0.01).Thedurationsofnauseaandvomitingof1,2,3,4timesinthethyroidectomygroupwerealsosignificantlylongerthanthoseintheLCgroup(P<0.01).Therewasapositivecorelationbetweenthenauseaandvomitingandthechangesofbloodflowvelocityorbloodflow(changeofbloodflowvelocity:rs=0.697,P=0.03;changeofbloodflow:rs=0.897,[DOI]10.7507/1007-9424.20130230【作者单位】1.湖北医药学院附属东风医院普外科(湖北十堰442008);2.皖南医学院附属弋矶山医院普外科(安徽芜湖241002)【通信作者】房淑彬,E—mail:husstome2000@yahoo.com.ca【作者简介】孙少华(1978年一),男,湖北省十堰市人,医学硕士,副主任医师,主要研究方向为甲状腺疾病的诊疗,E—mail:ssh.2222@163.tom。中国普外基础与临床杂志2013年8月第20卷第8期ChinJBasesCli...