基础区学中国组织工程研究与缶床康复第11卷第3，期2007—08—05出版JournalofClinicalRehabilitativeTissueEngineeringResearchAugust5J2007V01．11，No．31钛网结合表面植骨修复先天性脊椎裂陈文君，李凤霞，于新忠，尹绍猛，刘峰，伞有利，宋雯ChengdeHospital，067000，cheNnogdaehTitaniumalloynetandsurfacegraftforrepairofcongenitalspinalbifidaHebeiAbstractProvince．ChinaChenWen-jun，Associatechiefphysician．ChengdeNorthHospital．Chengde067000，HebeiProvince．Chinacdchenwenjun@163COmReceived：2007—05—12Accepted：2007·06—04AIM：ToapplylhetitaniumalloyRelcombinedwithbonegraftonitssurfacetorestorecongenitalspinaIbifidafSB)．andobservetheIong—IermeffectonbonedefectsthroughthefoIlow—uD．METHODS：FromApri2003loApriJ2006。36SBpatientswerechosenfromDepartmentofSpinaSurgeryinChengdeNorthHospital．including12dominantcasesand24recessivecasesTheyalIreceivedvertebralcolumnsurgeryloexposethevertebralplateonboth‘sidesofIesionviathecentralposteriorvertebralcolumnapproach．DominantcasesweretreatedwithspinalmeningesandspinaIcordreturning，thensac—neckligationwasperformed；Recessivecaseswereusedtoseparatetheduramaterandsurroundingsofttissueadhesionbelt．Thepropertitaniumnetmouldwasusedtocoverbonedefectsurface．foIlowedbybilateraIfixations．andtheartificiafboneortheautogenousbonewascutintotinyparticles，whichwereimplantedonsurface．。RESULTS：Thirty—s．xpatientswereallinvolvedintheresulIanalysis．①Long—lermeffectthroughfoIlow--ups：A¨thepatientswerefoIlowedupfornOlessthan12months．In24recessiveSBpatients。lumbagowasfoundtodisappearafteroperationandnervereappear．theyrecoveredtowork2monthsJater；In12dominantSBpatients．therewasnonervoussystemsymptomfoundin8casesofspinaImeninogocele．accompanyingthatfecesandurinetogetherwithmuscularstrengthofIowerIimbswereallnormal。inother3casescomplicatedwithpartlyprotrusionincaudaequinanerve．enuresislandIowerlimbdisorderdidnotrelapse．nomassformedintheincisionandsurroundingtissue．FecalandurinarydysfunctionandlowerIimbdisorderwerenotobviouslyimprovedinonecasecomplicatedwithwholeprotrusionincaudaequinanerve．②Bonehealingingraftarea：Boneunionformedtightlyinbonegraftarea，withoutbonedisunion，nearthrosisformationandcomplication．(∞HostresponseandmateriaIresponse：Low-gradefeveroccurredin3casesandwasimprovedbysymptomatictreatment；Thetitaniumnetcombinedwithhostbonetightly，havingnorejectionorelectrolysisreaction．’CoNCLUSIoN：BonegraftonthesurfaceoftitaniumalloynetIseffectivetorestoreSB。tightosseousiunctionformsbetweengraftboneandhostbone．resultinginsupportforshorttermandconfluenceforlongteml．ThismethodcanbeappliedforboththedominantandrecessiveSBpatients．．ChenWJ，LiFX，YuXZ，YinSM，LiuF，SanYL，SongWTitaniumalloynetandsurfacegraftforrepairofcongenitalspinalbifidaZhongguoZuzhiGongchengYanjiuyuLinchuangKangfu2007；11(31)：6274-6276{China)雎删抛zgJck￡com，删ck￡蚓oumaJ，upaIes妇7-31肥1k-6274(ps)．pdf]摘要．一目的：应用钛网结合表面植骨技术修复先天性脊椎裂骨缺损，随访观察其远期骨修复效果。方法：选择2003—04／2006—04承德北方医院脊柱外科收治的脊椎裂患者36例，其中显性脊椎裂12例，隐性脊椎裂24例，均采用脊柱后正中入路、显露病变两侧的椎板，显性者要先还纳脊膜脊髓结扎囊颈；隐性者分离硬膜与周围软组织的粘连带。选相适宜的钛网(天津市康利民医疗器械有限公司生产)塑形后敷盖骨缺损表面，两侧给予固定，将人工骨或自体骨剪成细小颗粒状植入表面。结果：36例均完成治疗进入结果分析。④...
