目 录摘 要..............................................................IAbstract...........................................................II第一章 产品概述....................................................11.1 产品名称及分子式、分子结构..................................1产品药理作用及适应症............................................1 药代动力学.....................................................2第二章 工艺流程概述.................................................4生产工艺流程框图................................................42.2 RIN-1 的合成.................................................42.3 RIN-2 的合成.................................................6伏立康唑的合成..................................................7成品伏立康唑（RIN）质量标准.....................................9第三章 物料衡算....................................................10计算方法与原则.................................................10还原（氢解脱氯）的物料衡算.....................................123.3 成盐的物料衡算.............................................27游离的物料衡算.................................................34第四章 能量衡算....................................................474.1 计算方法与原则.............................................47热量衡算基础数据的计算和查取...................................494.3 还原工段物料衡算...........................................544.4 成盐工段能量衡算...........................................624.5 拆分工段物料衡算...........................................67第五章 设备选型....................................................725.1 选型方法和原理.............................................725.2 部分标准设备的选型.........................................74第六章 车间布置形式...............................................84车间布置的方法与原理...........................................84厂房布置.......................................................84车间设备布置..............................................
