年产10吨透明质酸生产车间的初步工艺设计

毕 业 设 计（论文） 毕业设计说明书汉字摘要 毕业设计说明书外文摘要 本设计为以高产菌为出发菌株年产10吨透明质酸生产车间初步设计。主要包括到工艺流程分为一级发酵、一次沉淀、溶解、过滤、二次沉淀、脱水、干燥等。生产菌株实行现在最高产兽疫链球菌发酵。发酵时实行兽疫链球菌进行一级好氧发酵，发酵液用乙醇进行沉淀，去离子水进行溶解，丙酮进行脱水,电加热进行干燥。设计包含物料衡算，设备计算和选型，水、电、汽估算，工艺流程设计、主要生产车间（发酵和提取）设计、车间设备平面布置设计等内容。设备计算与选型是依照产量经过计算来确定设备型号和尺寸。车间布置是对生产设备和其它设施进行合理布置并确定车间大小。 关键词 透明质酸 发酵 提取 物料衡算 设备计算和选型 车间布置 Title An annual output of 10 tons of hyaluronic acid production plant preliminary design Abstract This is designed to high-yielding strains of bacteria as a starting annual output tons of hyaluronic acid production plant preliminary design. Mainly related to proce divided into a fermentation, a precipitate, dissolving, filtering, secondary sedimentation, dehydration, drying. Producing strains currently used most productive fermentation of Streptococcus. Fermentation using Streptococcus conduct an aerobic fermentation, Fermentation broth by precipitation with ethanol, dissolved in deioniz water, dehydrated in acetone, heated and dried.The design process including technolog of oxytetracycline production, main production workshops (fermentation and extraction), the ground plan of workshop and equipment layout design, material accounting, calculation and selection of equipment, water, electricity, steam, such estimates of the content. Equipment models is to determine the type and size of equipment by calculating the volume of materials. Workshop set is to reasonably furnish the production equipment and other facilities and to determine a reasonable s workshop. Key W...