中国临床康复箬9卷箬9期2005—03—07出版ChineseJournalofClinicalRehabilitation,March72005Vo1.9No9多发性硬化:视神经脊髓型核磁共振的特征及其功能干预的新方法邢建丽,王苏151·综述·邢建丽,王办,解放军北京军区总医院干部病房三科,北京市100700邢建丽,女,1968年生,山西省太原市人,汉族,1991年山西医科大学毕业,学士,主治医师,主要从事脑血管病、老年病的研究XJL2003BJ@tom.cam电话:+86.10.64031738中图分类号:R743文献标识码:B文章编号:1671—5926(2005)09—0151—03收稿日期:2004—12—02修回日期:2004—12—23(04/SN/Y)Multiplesclerosis:charactersofmagneticresonanceimagingofopticnerveandspinalcordandthenewmethodofinterventionXingJJan.1iWangSuXingJJan.1iWangSuThirdDepartmentofCadre’sWard.GeneralHospitalofBeiiingMilitaryAreaCommandofChinesePLA,Beiiing100700ChinaCorrespondenceto:XingJian·li,Attendingphysician,ThirdDepartmentofCadre’sWard.GeneralHospitalofBeiiingMilitaryAreaCommandofChi.nesePLA,Beiiing100700,ChinaXJ12003BJ@tom.camReceived:2004—12—02Accepted:2004一l2—23Abstract0BJECTⅣE:Multiplesclerosis(MS)iscommonandisofteninvolvedi11spinaleordandopticnerveinChinaandJapan.Earlydiagnosisanddetectionofsub.clinicalfocusandtimelyinterventionareveryimportantforpreventingthedevelopmentofillnessandamelioratingthefunctionalimpairment.Inthispaper.wereviewthelatestinvestigations.、DATAS0URCES:Usingthekeyterms“multiplesclerosis.epidemiology.diagnosis.treatment.wesearchedtheMEDLINEdatabasefortherelevalitarticlesaboutdiagnosisandtherapyforMSinEnglishfromJanuaD'1993toApril2004.Meanwhile.usingthesamekeytermsinChinese.wesearcherltheWanfangdatabaseduringthesameperiod.STUDYSELECT10N:A11articleswereselectedfirstly.thosewererelevanttothediagnosisandtherapyofmultiplesclerosisinrecentfivevearswerecollected.ThearticlesofsummarizationsandMetaanalysiswereexcludedandtherestfu11textwaslookedup.DATAEXTRACT10N:Atotalof30articleswerecollected.Twentyarticlesofthemwereselectedandtenofthemwereexcludedbecauseofduplicatedresearches.DATASYNTHESIS:Sevenof20articlesfocusedonimagingcharacteristicsofMs.7articleswereaboutneuroimmunology,3aboutelectromy。graphy(EMG)andevokedpotentlaland3aboutthetreatmentofMS.C0NCLUS10N:MSisaninflammatorydemyelinatingdiseasenthecentrall1en’OUSsystem(CNS).buttheperipheralnervoussystemCalloftenbein.、olvedatmeantime.EMGandevokedpotentialareusefultestmethodsthatnlavfindsub.clinicalfoCUSandevaluateprognosisofmultiplesclerosis.TheJapanesereportsaboutneuroimmunologyprovideusanewthinkingondiag·llOSiSofmultiplesclerosis.HematopoieticstemcelltransDlantati0nisamewtherapeuticstrategyforpatientswithdamagedaxis·cylinderandrecurrentMS.Xing儿.WangSMultiplesclerosis:charactersofmagneticresonanceimagingofopticnerveandspinalcordandthenewmethodofinterventionZhongguoLinchuangKanE[u2005;9{9l:151—3(Chinal邢建丽.王苏多发性硬化:视神经脊髓型核磁共振的特征及其功能干预的新方法⋯中国临床康复,2005,9{9l:151—31wwwzglckfcaml摘要目的:多发性硬化病灶多发,在中国和日本主要是以脊髓和视神经受累多见:早期诊断和发现亚l性床病灶并及时干预,对阻止病情发展和改善功能障碍至关重要。文章就以上各方面的最新研究做一综述一资料来源:应用计算机检索Medline1993一叭/2004—04与多发性硬化的诊断与治疗相关的文章,检索词”multiplesclerosis,epidemiologv,di.agnosis,treatment”,并限定文章语言为English。同时通过手工和计算机对国内万方数据库2000一叭/2004—04的相关文章进行检索,检索...