精品文档---下载后可任意编辑NM23、Survivin 在大肠癌组织中的表达与临床意义的开题报告摘要背景：大肠癌是最常见的消化系统肿瘤之一，早期诊断和治疗对改善患者预后至关重要。NM23 和 Survivin 是与肿瘤发生、进展密切相关的分子，其在大肠癌中的表达与患者预后关系尚不清楚。目的：本讨论旨在探究 NM23 和 Survivin 在大肠癌组织中的表达及其与临床病理特征和预后的关系，为大肠癌的诊治提供参考。方法：采纳免疫组化技术检测大肠癌患者组织 NM23 和 Survivin 的表达情况，并与患者临床病理特征及预后进行相关分析。预期结果：本讨论估计能够从分子水平上探究 NM23 和 Survivin 在大肠癌中的作用机制，为大肠癌的诊治提供新的分子靶点和治疗方法。结论：NM23 和 Survivin 在大肠癌组织中的表达与患者预后密切相关，具有重要的临床意义，可能成为预测和治疗大肠癌的有力工具。关键词：NM23；Survivin；大肠癌；免疫组化技术；预后AbstractBackground: Colorectal cancer is one of the most common digestive system tumors, early diagnosis and treatment are crucial for improving the prognosis of patients. NM23 and Survivin are molecules closely related to tumor occurrence and development. Their expression in colorectal cancer and the relationship with patient prognosis are still unclear.Objective: This study aims to explore the expression of NM23 and Survivin in colorectal cancer tissues and their relationship with clinical pathological features and prognosis, providing reference for the diagnosis and treatment of colorectal cancer.Methods: Immunohistochemical technique was used to detect the expression of NM23 and Survivin in colorectal cancer tissues, and their correlation with clinical pathological features and prognosis was analyzed.Expected results: This study is expected to explore the role of NM23 and Survivin in colorectal cancer at the molecular 精品文档---下载后可任意编辑level, providing new molecular targets and treatment methods for the diagnosis and treatment of colorectal cancer.Conclusion: The expression of NM23 and Survivin in colorectal cancer tissues is closely related to patient prognosis and has important clinical significance. They may become powerful tools for predicting and treating colorectal cancer.Key words: NM23; Survivin; Colorectal cancer; Immunohistochemical technique; Prognosis
