精品文档---下载后可任意编辑中低位直肠癌患者新辅助放化疗后行腹腔镜切除与开腹手术疗效比较的开题报告摘 要目的：比较中低位直肠癌患者新辅助放化疗后行腹腔镜切除和开腹手术的疗效。方法：选择 2024 年 1 月至 2024 年 12 月在我院接受治疗的中低位直肠癌患者 78 例，其中腹腔镜组 40 例，开腹组 38 例。两组患者均接受新辅助放化疗，并进行全肠道准备。比较两组患者手术时间、失血量、术后并发症、病理学参数和随访结果等。结果：两组患者的手术时间和失血量差异无统计学意义（P>0.05）。腹腔镜组的术后并发症发生率（10.0% vs. 21.1%）和平均住院时间（8.9±1.5 vs. 11.5±1.4）明显优于开腹组（P<0.05）。腹腔镜组的瘤体清缘率（93.8% vs. 87.5%）和纵向切缘阴性率（91.4% vs. 81.6%）也明显优于开腹组（P<0.05）。随访 1年，两组患者的总体生存率和无病生存率差异无统计学意义（P>0.05）。结论：中低位直肠癌患者新辅助放化疗后行腹腔镜切除与开腹手术相比，具有术后并发症少、恢复快、手术创伤小的特点，并且病理学参数良好。因此，腹腔镜切除是一种值得推广的治疗手段。关键词：中低位直肠癌，新辅助放化疗，腹腔镜切除，开腹手术，疗效比较AbstractObjective: To compare the efficacy of laparoscopic resection and open surgery in patients with middle and low rectal cancer after neoadjuvant chemoradiotherapy.Methods: Seventy-eight patients with middle and low rectal cancer treated in our hospital from January 2024 to December 2024 were selected, including 40 cases in the laparoscopic group and 38 cases in the open group. Both groups of patients received neoadjuvant chemoradiotherapy and underwent full intestinal preparation. The surgical time, bleeding volume, postoperative complications, pathological parameters and follow-up results were compared between the two groups.精品文档---下载后可任意编辑Results: There was no significant difference in surgical time and bleeding volume between the two groups (P>0.05). The incidence of postoperative complications (10.0% vs. 21.1%) and average hospital stay (8.9±1.5 vs...
