精品文档---下载后可任意编辑降糖明目汤对视网膜促血管生成相关因子的影响的开题报告摘要:本讨论旨在探究降糖明目汤对视网膜促血管生成相关因子的影响。通过建立高脂饮食致糖尿病大鼠模型,观察降糖明目汤对视网膜组织中VEGF、bFGF 以及 TGF-β1 等促血管生成相关因子的调节作用。结果显示,与模型组相比,给予降糖明目汤干预后可以有效抑制视网膜VEGF、bFGF 以及 TGF-β1 等促血管生成相关因子的表达,且与空白对比组比较,降糖明目汤组视网膜 VEGF、bFGF 以及 TGF-β1 等促血管生成相关因子表达水平均有明显下降。关键词:降糖明目汤;视网膜;促血管生成相关因子;糖尿病Abstract:This study was conducted to investigate the effects of Jiang Tang Ming Mu Tang on retinal angiogenic factors in a rat model of diabetes induced by high-fat diet. The regulatory effects of Jiang Tang Ming Mu Tang on VEGF, bFGF, and TGF-β1, which are related to retinal angiogenesis, were observed. The results showed that compared with the model group, Jiang Tang Ming Mu Tang effectively inhibited the expression of VEGF, bFGF, and TGF-β1 in the retinal tissues, and compared with the blank control group, the expression levels of VEGF, bFGF, and TGF-β1 in the retinal tissues of the Jiang Tang Ming Mu Tang group were significantly decreased.Keywords: Jiang Tang Ming Mu Tang; retina; angiogenic factors; diabetes.