精品文档---下载后可任意编辑非小细胞肺癌临床预后模型的探讨的开题报告摘要：肺癌是常见的恶性肿瘤之一，其中非小细胞肺癌占肺癌的 80%-85%。肺癌化疗、手术和放疗等治疗手段虽然可以延长患者的生存期，但患者的临床预后仍然不容乐观。因此，本讨论旨在建立非小细胞肺癌临床预后模型，预测患者的生存期，并探讨临床因素对非小细胞肺癌患者生存期的影响。本讨论采纳回顾性讨论方法，选取中国医学科学院肿瘤医院 2024 年至 2024 年间收治的 500 例非小细胞肺癌患者作为讨论对象。通过统计和分析患者的基本信息、病理学特征、治疗情况、化疗方案等数据，并运用 COX 回归模型建立非小细胞肺癌临床预后模型。同时，利用 Kaplan-Meier 生存分析法绘制生存曲线，比较不同因素对患者生存期的影响。估计讨论结果将有助于了解非小细胞肺癌患者的生存期及其相关因素，提高临床医生对非小细胞肺癌患者的治疗策略和预后评估水平，从而更好地指导非小细胞肺癌患者的治疗和管理。关键词：非小细胞肺癌；临床预后模型；COX 回归模型；生存期分析；临床因素Abstract:Lung cancer is one of the most common malignant tumors, with non-small cell lung cancer accounting for 80%-85% of all lung cancers. Although chemotherapy, surgery, and radiation therapy can extend the survival time of lung cancer patients, the clinical prognosis of patients is still not good. Therefore, this study aims to establish a clinical prognostic model for non-small cell lung cancer, predict the survival time of patients, and explore the impact of clinical factors on the survival time of non-small cell lung cancer patients.This study used a retrospective research method and selected 500 non-small cell lung cancer patients admitted to the Cancer Hospital of the Chinese Academy of Medical Sciences between 2024 and 2024 as the study subjects. The basic information, pathological characteristics, treatment status, chemotherapy regimen and other data of patients were statistically analyzed, and a COX regression model was used to establish a clinical prognostic model for non-small cell lung cancer. At the same time, Kaplan-Meier survival analysis was used to draw survival curves and compare the impact of different factors on patient survival.It is expected that the results of this study will help to understand the survival time and related factors of non-small cell lung cancer patients, improve the treatment strategy and prognostic evaluation level of clinical doctors for non-small cell lung cancer patients, and better guide the treatment and management of non-small cell lung cancer patients.Keywords: Non-small cell lung cancer; clinical prognostic model; COX regression model; survival analysis; clinical factors.
