·248·眼科新进展2006年4B第26卷第4期RecAdvOphthalmolV01．26No．4April2006作者简介：陈琛，女，1977年出生，河北人，硕士研究生。联系电话：13810390307；E—mail：cajJq@163．cornAboutCHENChen：Female，bomin1977，MasterofMedicine．Tel：1381(Bcal307；E-rmil：m——jiq@163．(xln收稿日期：2006—01—02修回日期：2006—02—16本文编辑：徐刚珍6基金项目：国家自然科学基金资助(编号：30270356)作者单位：100730北京市，首都医科大学附属同仁医院眼科中心(陈琛，林丁)；100054北京市，首都医科大学生物医学工程学院(刘晓华，刘志成。张昆亚，宋红芳)通讯作者：林丁，E—mail：dlinoph@yahoaCOIn．cn；刘志成，E—mail：zcliu@cpurns．edu．anReceiveddate：Jan2，2006Accepteddate：Feb16，2006Fmmdationiron：NationalNaturalScienceFoundationofCtfma(No：30270356)FromtheDepartmentofOphthal—mology，theTongrenHospitalofCapitalUnizersityofMedicalSci—cHce(CHENChert，LINDing)，Bei一，ing100730，China；nFP勘medicalEngineeringCollegeofthe＆历碰Universityo，MedicalScience(LIUXiaoHua．LIUZhi-C'h∞g．2HANGKun-Ya，S)NGHong-Fang)，Beijing100054．ChinaR嘲H商bkl狙lthor：LINI]ir】g，E-mail：dlinoph@、I；l}m．oⅫ．oa；LIUZhi—Chug，F．．厂rmil：zclin@cptrm．edu．cn基于定量瞳孔阻滞力仿真实验的虹膜组织生物力学特性分析△陈琛刘晓华林丁刘志成张昆亚宋红芳Anexperimentresearchbasedonsimulatingpupillaryblockingforcetoanalyzemechani—caIpropertiesofiristissuequantitatiVelyCHENChen，LIUXiao-Hua，LINDing，LIUZhi-Cheng，ZHANGKun-Ya，SONGHong．Fang【Keywords】iris；puptllaryblockingforce；strainofsurface；radiusofcurva-ture；differentialpressurebetweentheanteriorandposteriorchamber；prima-ryangle-closureglaucoma【Abstract】ObjectiveToanalyzethemechanicalpropertiesofiristissuebasedonsUmulatingpupillaryblockingforceinordertofindtherelationbe-tweentheparameteroftheirispropertyandthedifferenttalpressurebe—tweentheanteriorandposteriorchamber．MethodsWeappliedsimulatingpupillaryblockingdevicetosimulatethepupillaryblockingforceandusedliquidloadingapparatustostmulaLtethedifferentialpressurebetweenthean-teriorandposteriorchamber．ThenweloadedpressureOlltheintegrativeiristoquantitativelyanalyzetherelationshipbetweenthePressureoftheanteriorandposteriorchamberwiththechangeofthestrainofirissurfaceandthem-diusofiriscurvatureunderthepupillaryblockingforce．ResultsThemodelwassinailarwiththeclinicalphenomena．Thismodelwasmoretruetonaturethanthemodelthatwesuturedthepupilbefore．Usingthemodel，wegainedtheequationcongatningthestrainofirissurface(8)，theradiusofiriscurva-ture(／-)andthedifferentialpressurebetweentheanteriorandposteriorchamber(AP)．Theequationofdand△Pwas△P=boe。1。(bn=3．3373，b1=30．3909)．Theequationofrand△Pwas／-=e(bo+bl馏’(bo=0．4761，b1=21．66043)．Werealizedthequantitatireanalysisanddescribedtherelation-shipbetweenthedifferentpupillaryblockingforceandthedifl'erenttalpres-surebetweentheanteriorandposteriorchamber．ConclusionWerealizethequantttattvemeasurementforsmalldynamicparameterofsofttissue．Thestrainofsurfaceandtheradiusofcurvatureoftheirisisthepropertyparam-eterthatcanbemeasuredj扬eycanrefiectthechangeofthedifferentialpressurebetweentheanteriorandposteriorchambersensitively．Theradiusofcurvatureofthehighestspotoftheiriscanbemeasuredeasilyinclinic．Soitcanhelpusdiagnoseandtreattheglaueonlaearly．1RecAdvOphthalmol2006；26(4)：248．252【中图分类号】R773【文献标识码】A【文章编号】1003—5141(2006)04—0248—05【关键词】虹膜；瞳孔阻滞力；面应...
